HitPredict

Interactor 1: VINC (O46037)
Vinculin
Gene: VINC

Interactor 2: FKB12 (P48375)
Peptidyl-prolyl cis-trans isomerase Fkbp12 (PPIase Fkbp12) (EC 5.2.1.8) (12 kDa FK506-binding protein) (12 kDa FKBP) (Macrolide-binding protein) (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase)
Gene: Fkbp12

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	14605208, 38944040
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 961 Dm			1 108
+	Dm
		234593 VINC_DROME (1-961): 0: 835: 100.00		Q9V3V2_DROME (3-107): 1.17e-48: 155: 48.60
+	Dm
		234606 VINC_DROME (1-961): 0: 835: 100.00		Q9VGK3_DROME (1-108): 6.87e-43: 138: 41.28
+	Dm
		234621 VINC_DROME (1-961): 0: 835: 100.00		FKB59_DROME (3-106): 9.98e-15: 70.1: 24.07
+	Hs
		613335 VINC_HUMAN (1-805): 3.68e-92: 318: 29.02		FKBP4_HUMAN (2-108): 5.65e-15: 70.9: 27.93