HitPredict

Interactor 1: SNX3 (O60493)
Sorting nexin-3 (Protein SDP3)
Gene: SNX3

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 162 Hs			1 304
+	Hs
		802779 SNX7_HUMAN (8-150): 8.2e-37: 132: 30.56		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		1167842 SNX9_HUMAN (1-145): 4.92e-32: 121: 20.53		DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35
+	Hs
		1167815 SNX33_HUMAN (1-162): 6.94e-30: 115: 23.64		DNMBP_HUMAN (119-293): 5.7e-46: 168: 29.35
+	Hs
		234938 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924951 SNX12_HUMAN (5-161): 8.43e-52: 164: 80.26		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		275222 SNX18_HUMAN (6-149): 2.94e-34: 127: 23.65		GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17
+	Hs
		581079 SNX7_HUMAN (8-150): 8.2e-37: 132: 30.56		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		234898 SNX3_HUMAN (1-162): 5.77e-58: 179: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		924952 SNX7_HUMAN (8-150): 8.2e-37: 132: 30.56		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924801 SNX18_HUMAN (6-149): 2.94e-34: 127: 23.65		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		557828 SNX12_HUMAN (5-161): 8.43e-52: 164: 80.26		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Mm
		1141156 SNX18_MOUSE (21-149): 5.73e-32: 121: 24.06		GRB2_MOUSE (135-297): 1.43e-25: 103: 15.67
+	Hs
		581087 SNX11_HUMAN (20-148): 4.98e-30: 111: 33.59		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		557829 SNX7_HUMAN (8-150): 8.2e-37: 132: 30.56		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		1078933 SNX6_HUMAN (1-148): 1.05e-30: 116: 19.43		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		1078937 SNX5_HUMAN (3-149): 4.75e-30: 114: 20.00		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87