Protein: RRP45
Exosome complex component RRP45 (Ribosomal RNA-processing protein 45)

Gene: RRP45
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: Q05636

Gene Ontology (top 5):
GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

809587

RRP41
Exosome complex component SKI6

14

20

Small-scale

0.986

High

865419

CSL4
Exosome complex component CSL4

12

11

Small-scale

0.978

High

984317

RRP44
Exosome complex exonuclease DIS3

11

19

Small-scale

0.977

High

860807

RRP46
Exosome complex component RRP46

9

20

Small-scale

0.970

High

630257

RRP43
Exosome complex component RRP43

8

2

Small-scale

0.967

High

754995

RRP4
Exosome complex component RRP4

7

20

Small-scale

0.962

High

984318

RRP40
Exosome complex component RRP40

6

11

Small-scale

0.945

High

816972

MTR3
Exosome complex component MTR3

5

2

Small-scale

0.922

High

982869

RRP5
rRNA biogenesis protein RRP5

3

7

High-throughput

0.817

High

984325

RRP6
Exosome complex exonuclease RRP6

12

11

Small-scale

0.757

High

984319

SKI7
Superkiller protein 7

8

7

Small-scale

0.748

High

984328

RRP42
Exosome complex component RRP42

6

17

Small-scale

0.730

High

979021

DHR1
Probable ATP-dependent RNA helicase DHR1

6

2

High-throughput

0.729

High

792580

UTP10
U3 small nucleolar RNA-associated protein 10

5

2

High-throughput

0.712

High

864436

MPP6
M-phase phosphoprotein 6 homolog

4

2

Small-scale

0.696

High

571917

SKI3
Superkiller protein 3

4

4

High-throughput

0.694

High

716207

SKI2
Antiviral helicase SKI2

4

13

High-throughput

0.694

High

715982

UTP20
U3 small nucleolar RNA-associated protein 20

4

2

High-throughput

0.691

High

755200

LRP1
Exosome complex protein LRP1

4

2

Small-scale

0.683

High

860738

UTP22
U3 small nucleolar RNA-associated protein 22

4

3

High-throughput

0.678

High

984306

RRP45
Exosome complex component RRP45

1

17

High-throughput

0.665

High

748701

ENP1
Essential nuclear protein 1

3

2

High-throughput

0.640

High

972908

IMA1
Importin subunit alpha

2

2

High-throughput

0.588

High

963174

RPA49
DNA-directed RNA polymerase I subunit RPA49

2

0

High-throughput

0.585

High

634768

KRR1
KRR1 small subunit processome component

2

2

High-throughput

0.584

High

810917

MTR4
ATP-dependent RNA helicase DOB1

2

13

Small-scale

0.584

High

979711

UTP14
U3 small nucleolar RNA-associated protein 14

2

3

High-throughput

0.584

High

984312

NOC4
Nucleolar complex protein 4

2

2

High-throughput

0.584

High

494960

HSP72
Heat shock protein SSA2

2

6

High-throughput

0.552

High

512730

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

743678

HMT1
Protein arginine N-methyltransferase 1

1

3

Small-scale

0.541

High

863171

NRD1
Protein NRD1

1

1

Small-scale

0.536

High

604617

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.493

High

688424

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.493

High

984323

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.480

High

630536

RRP7
Ribosomal RNA-processing protein 7

1

2

High-throughput

0.479

High

635643

PWP2
Periodic tryptophan protein 2

1

8

High-throughput

0.479

High

663324

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

707136

DCA13
Protein SOF1

1

5

High-throughput

0.479

High

711071

UTP11
U3 small nucleolar RNA-associated protein 11

1

2

High-throughput

0.479

High

728316

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.479

High

756785

UTP9
U3 small nucleolar RNA-associated protein 9

1

2

High-throughput

0.479

High

767417

UTP7
U3 small nucleolar RNA-associated protein 7

1

2

High-throughput

0.479

High

772674

UTP18
U3 small nucleolar RNA-associated protein 18

1

3

High-throughput

0.479

High

775388

FAF1
Protein FAF1

1

2

High-throughput

0.479

High

811556

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

2

High-throughput

0.479

High

816904

NOL10
Ribosome biogenesis protein ENP2

1

1

High-throughput

0.479

High

861025

UTP8
U3 small nucleolar RNA-associated protein 8

1

2

High-throughput

0.479

High

866052

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

866613

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

2

High-throughput

0.479

High

970465

UTP6
U3 small nucleolar RNA-associated protein 6

1

2

High-throughput

0.479

High

973670

UTP17
NET1-associated nuclear protein 1

1

14

High-throughput

0.479

High

978629

UTP5
U3 small nucleolar RNA-associated protein 5

1

7

High-throughput

0.479

High

979236

UTP15
U3 small nucleolar RNA-associated protein 15

1

4

High-throughput

0.479

High

983766

FCF1
rRNA-processing protein FCF1

1

2

High-throughput

0.479

High

984308

UTP13
U3 small nucleolar RNA-associated protein 13

1

8

High-throughput

0.479

High

984309

UTP21
U3 small nucleolar RNA-associated protein 21

1

12

High-throughput

0.479

High

984310

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

2

High-throughput

0.479

High

984311

RRP9
Ribosomal RNA-processing protein 9

1

8

High-throughput

0.479

High

984313

BFR2
Protein BFR2

1

2

High-throughput

0.479

High

984315

UTP4
U3 small nucleolar RNA-associated protein 4

1

8

High-throughput

0.479

High

984316

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

2

High-throughput

0.479

High

984320

UTP16
U3 small nucleolar RNA-associated protein 16

1

2

High-throughput

0.479

High

984321

BMS1
Ribosome biogenesis protein BMS1

1

2

High-throughput

0.479

High

984322

FCF2
rRNA-processing protein FCF2

1

2

High-throughput

0.479

High

984324

SAS10
Something about silencing protein 10

1

3

High-throughput

0.479

High

984326

YRA1
RNA annealing protein YRA1

1

3

Small-scale

0.479

High

984327

UTP12
U3 small nucleolar RNA-associated protein 12

1

11

High-throughput

0.479

High

984329

NOP56
Nucleolar protein 56

1

7

High-throughput

0.479

High

984330

NOP58
Nucleolar protein 58

1

7

High-throughput

0.479

High

984331

RRP12
Ribosomal RNA-processing protein 12

1

2

High-throughput

0.479

High

984332

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.479

High

837353

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

3

High-throughput

0.470

High

799854

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

984333

PNO1
Pre-rRNA-processing protein PNO1

1

0

Small-scale

0.458

High

376931

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

High-throughput

0.445

High

492438

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

560799

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.445

High

680994

HS104
Heat shock protein 104

1

3

High-throughput

0.445

High

695520

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.445

High

754709

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.445

High

761312

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

769474

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

471835

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.437

High

478990

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.437

High

554745

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

424711

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.407

High

478528

HSP77
Import motor subunit, mitochondrial

1

6

High-throughput

0.407

High

544421

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

588227

HSP60
Heat shock protein 60, mitochondrial

1

1

High-throughput

0.407

High

705654

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.407

High

766214

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.407

High

837290

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

3

High-throughput

0.407

High

984307

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

11

High-throughput

0.407

High

710499

YBF5
Deoxyribonuclease Tat-D

1

0

High-throughput

0.269

Low

812539

ENT3
Epsin-3

1

0

High-throughput

0.269

Low

345249

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.249

Low

568908

HPR1
THO complex subunit HPR1

1

0

Small-scale

0.249

Low

649929

CDC15
Cell division control protein 15

1

0

High-throughput

0.249

Low

556301

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

810151

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

984314

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024