Interactor 1: GMDS (O60547)
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)
Gene: GMDS

Interactor 2: GMDS (O60547)
GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD)
Gene: GMDS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GDP_Man_Dehyd~GDP_Man_Dehyd
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007219 - Notch signaling pathway
GO:0008446 - GDP-mannose 4,6-dehydratase activity
GO:0019673 - GDP-mannose metabolic process
and 3 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 372
Hs

1 372
+ Dm
+ Ce
+ Ce
+ At
+ At
+ At
+ Hs
+ Dm
+ Sc
+ Ec
+ Cj
+ Ec
+ At

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Last updated: 15 Jul 2024