Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: KNL1 (Q8NG31)
Kinetochore scaffold 1 (ALL1-fused gene from chromosome 15q14 protein) (AF15q14) (Bub-linking kinetochore protein) (Blinkin) (Cancer susceptibility candidate gene 5 protein) (Cancer/testis antigen 29) (CT29) (Kinetochore-null protein 1) (Protein CASC5) (Protein D40/AF15q14)
Gene: KNL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.733

The method score is based on:

Property Details
Experiments 25852190, 22000412, 17981135, 21199919, 20220147
Identification Methods affinity chromatography technology, x-ray crystallography, pull down, two hybrid, classical fluorescence spectroscopy, isothermal titration calorimetry, molecular sieving, mass spectrometry studies of complexes, circular dichroism, nuclear magnetic resonance and 1 others

more...

Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0051301 - cell division
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1050
Hs

1 2342
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024