HitPredict

Interactor 1: BUB1B (O60566)
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (hBUBR1) (Mitotic checkpoint kinase MAD3L) (Protein SSK1)
Gene: BUB1B

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 779
+	Hs
		1082035 PKN2_HUMAN (158-1044): 3.09e-133: 429: 11.30		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682210 AKT2_HUMAN (629-1044): 6.22e-114: 362: 12.59		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		566481 KPCA_HUMAN (576-1044): 3.3e-109: 356: 13.75		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		682023 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1039170 KCC2D_HUMAN (764-1021): 2.99e-96: 316: 16.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		210982 BUB1_HUMAN (53-1042): 1.59e-170: 531: 19.04		RASA1_HUMAN (72-437): 2.74e-44: 174: 11.32
+	Hs
		1039032 KCC2G_HUMAN (764-985): 5.89e-62: 223: 19.05		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Mm
		57863 KALRN_MOUSE (94-1029): 2.11e-121: 413: 11.32		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Mm
		57840 KALRN_MOUSE (94-1029): 2.11e-121: 413: 11.32		CYTSA_MOUSE (320-643): 7.93e-41: 164: 12.20
+	Hs
		1077849 MYLK_HUMAN (169-1019): 5.83e-116: 396: 11.48		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		681831 AKT1_HUMAN (687-1044): 9.94e-111: 354: 13.46		GAB1_HUMAN (52-611): 6.48e-53: 197: 13.92
+	Rn
		1144020 AKT3_RAT (687-1044): 5.9e-111: 354: 14.02		CAPS1_RAT (11-428): 1.59e-46: 181: 10.23
+	Hs
		566377 KPCA_HUMAN (576-1044): 3.3e-109: 356: 13.75		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		1022390 KCC2D_HUMAN (764-1021): 2.99e-96: 316: 16.61		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		787158 KCC2D_HUMAN (764-1021): 2.99e-96: 316: 16.61		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27
+	Mm
		659464 KCC2B_MOUSE (764-985): 3.6e-60: 217: 17.75		CNKR2_MOUSE (1-468): 7.51e-48: 185: 14.40
+	Rn
		506782 KCC2A_RAT (764-985): 1.69e-60: 216: 17.75		CNKR2_RAT (1-468): 2.97e-47: 183: 14.20
+	Rn
		506741 KCC2A_RAT (764-985): 1.69e-60: 216: 17.75		CAPS1_RAT (11-428): 1.59e-46: 181: 10.23
+	Hs
		1334862 KCC2A_HUMAN (764-985): 1.69e-60: 216: 17.75		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		787157 KCC2G_HUMAN (764-985): 5.89e-62: 223: 19.05		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27