Protein: NRX1A
Neurexin-1 (Neurexin I-alpha) (Neurexin-1-alpha)

Gene: NRX1A, Nrxn1
Organism: Mus musculus
Interactions: 98
UniProt ID: Q9CS84

Gene Ontology (top 5):
GO:0005246 - calcium channel regulator activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005886 - plasma membrane
GO:0006904 - vesicle docking involved in exocytosis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1223712

DLG4
Disks large homolog 4

3

20

High-throughput

0.633

High

1222470

NXPH1
Neurexophilin-1

1

5

High-throughput

0.618

High

1298050

MGLYR
Metabotropic glycine receptor

1

5

High-throughput

0.618

High

1423793

NRX1A
Neurexin-1

1

15

High-throughput

0.618

High

981233

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

2

1

Small-scale

0.584

High

1423799

DLGP1
Disks large-associated protein 1

2

1

High-throughput

0.584

High

1423800

SRCN1
SRC kinase signaling inhibitor 1

2

1

High-throughput

0.571

High

64328

KCNB2
Potassium voltage-gated channel subfamily B member 2

1

11

High-throughput

0.479

High

205306

ANXA8
Annexin A8

1

2

High-throughput

0.479

High

205686

CTND2
Catenin delta-2

1

6

High-throughput

0.479

High

312904

BSN
Protein bassoon

1

5

High-throughput

0.479

High

313206

LIN7C
Protein lin-7 homolog C

1

12

Small-scale

0.479

High

456926

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

479098

PDIA1
Protein disulfide-isomerase

1

2

High-throughput

0.479

High

518557

ANXA1
Annexin A1

1

2

High-throughput

0.479

High

572891

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.479

High

631796

MTAP2
Microtubule-associated protein 2

1

10

High-throughput

0.479

High

663173

GRIA2
Glutamate receptor 2

1

4

High-throughput

0.479

High

683951

MOES
Moesin

1

15

High-throughput

0.479

High

723525

SSR3
Somatostatin receptor type 3

1

7

High-throughput

0.479

High

772448

CALX
Calnexin

1

5

High-throughput

0.479

High

847005

H14
Histone H1.4

1

6

High-throughput

0.479

High

876554

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

1

3

High-throughput

0.479

High

900722

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

13

High-throughput

0.479

High

936158

AQP4
Aquaporin-4

1

1

High-throughput

0.479

High

945633

ACTN4
Alpha-actinin-4

1

9

High-throughput

0.479

High

954375

SNP25
Synaptosomal-associated protein 25

1

3

High-throughput

0.479

High

957891

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

1

High-throughput

0.479

High

990048

1433Z
14-3-3 protein zeta/delta

1

4

High-throughput

0.479

High

994456

PHB1
Prohibitin 1

1

4

High-throughput

0.479

High

995527

RL22
Large ribosomal subunit protein eL22

1

1

High-throughput

0.479

High

996630

1433T
14-3-3 protein theta

1

4

High-throughput

0.479

High

1021202

PKP1
Plakophilin-1

1

8

High-throughput

0.479

High

1033498

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

1043839

KCNB1
Potassium voltage-gated channel subfamily B member 1

1

11

High-throughput

0.479

High

1179616

PSD3
PH and SEC7 domain-containing protein 3

1

3

High-throughput

0.479

High

1190262

TEN4
Teneurin-4

1

20

High-throughput

0.479

High

1204096

KCD16
BTB/POZ domain-containing protein KCTD16

1

6

High-throughput

0.479

High

1221212

MYL6
Myosin light polypeptide 6

1

1

High-throughput

0.479

High

1223126

KTN1
Kinectin

1

9

High-throughput

0.479

High

1223837

DAG1
Dystroglycan 1

1

10

High-throughput

0.479

High

1274244

PLPR4
Phospholipid phosphatase-related protein type 4

1

1

High-throughput

0.479

High

1282931

FLNB
Filamin-B

1

17

High-throughput

0.479

High

1283498

SLIK5
SLIT and NTRK-like protein 5

1

9

High-throughput

0.479

High

1296596

Q8BH80
Vesicle-associated membrane protein, associated protein B and C

1

2

High-throughput

0.479

High

1296985

CKAP4
Cytoskeleton-associated protein 4

1

13

High-throughput

0.479

High

1297982

S39A6
Zinc transporter ZIP6

1

5

High-throughput

0.479

High

1298257

AMER2
APC membrane recruitment protein 2

1

1

High-throughput

0.479

High

1298772

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

2

High-throughput

0.479

High

1362340

LNX2
Ligand of Numb protein X 2

1

13

High-throughput

0.479

High

1408902

SYTL3
Synaptotagmin-like protein 3

1

4

Small-scale

0.479

High

1408904

SYTL2
Synaptotagmin-like protein 2

1

3

Small-scale

0.479

High

1408920

SYTL1
Synaptotagmin-like protein 1

1

3

Small-scale

0.479

High

1408948

RTN4
Reticulon-4

1

3

High-throughput

0.479

High

1423801

APBB1
Amyloid beta precursor protein binding family B member 1

1

2

High-throughput

0.479

High

1423802

VAPA
Vesicle-associated membrane protein-associated protein A

1

2

High-throughput

0.479

High

1423804

E41L3
Band 4.1-like protein 3

1

13

High-throughput

0.479

High

571110

RSSA
Small ribosomal subunit protein uS2

1

0

High-throughput

0.458

High

942138

WFS1
Wolframin

1

0

High-throughput

0.458

High

967634

RS7
Small ribosomal subunit protein eS7

1

0

High-throughput

0.458

High

993067

KCNJ3
G protein-activated inward rectifier potassium channel 1

1

0

High-throughput

0.458

High

1190234

PITM3
Membrane-associated phosphatidylinositol transfer protein 3

1

0

High-throughput

0.458

High

1222422

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.458

High

1281889

ASTRB
Protein Aster-B

1

0

High-throughput

0.458

High

1282872

LYRIC
Protein LYRIC

1

0

High-throughput

0.458

High

1341652

SNP47
Synaptosomal-associated protein 47

1

0

High-throughput

0.458

High

1362478

SYUB
Beta-synuclein

1

0

High-throughput

0.458

High

1423794

SCRN1
Secernin-1

1

0

High-throughput

0.458

High

1423797

NACHO
Novel acetylcholine receptor chaperone

1

0

High-throughput

0.458

High

1193922

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

15

High-throughput

0.445

High

1223163

GRID2
Glutamate receptor ionotropic, delta-2

1

4

Small-scale

0.445

High

693441

MAP4
Microtubule-associated protein 4

1

8

High-throughput

0.437

High

912311

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.437

High

932171

PRS6B
26S proteasome regulatory subunit 6B

1

1

High-throughput

0.437

High

999754

SPB5
Serpin B5

1

1

High-throughput

0.437

High

1135548

F171B
Protein FAM171B

1

2

High-throughput

0.437

High

1189705

FUBP2
Far upstream element-binding protein 2

1

2

High-throughput

0.437

High

1220132

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.437

High

1225798

H2B2E
Histone H2B type 2-E

1

3

High-throughput

0.437

High

1230042

CE170
Centrosomal protein of 170 kDa

1

3

High-throughput

0.437

High

1238017

SPKAP
A-kinase anchor protein SPHKAP

1

1

High-throughput

0.437

High

1298076

RAE1L
mRNA export factor

1

1

High-throughput

0.437

High

1341521

TRI29
Tripartite motif-containing protein 29

1

4

High-throughput

0.437

High

1362935

LRC59
Leucine-rich repeat-containing protein 59 [Cleaved into: Leucine-rich repeat-containing protein 59, N-terminally processed]

1

5

High-throughput

0.437

High

1408967

RRBP1
Ribosome-binding protein 1

1

12

High-throughput

0.437

High

1423722

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

1

High-throughput

0.437

High

1423795

CISY
Citrate synthase, mitochondrial

1

3

High-throughput

0.437

High

1423798

RUFY3
Protein RUFY3

1

5

High-throughput

0.437

High

584830

NDKA
Nucleoside diphosphate kinase A

1

0

High-throughput

0.249

Low

868630

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.249

Low

926892

STMN1
Stathmin

1

0

High-throughput

0.249

Low

980670

H4
Histone H4

1

0

High-throughput

0.249

Low

992678

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.249

Low

1274547

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.249

Low

1408737

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

1423796

LSM12
Protein LSM12

1

0

High-throughput

0.249

Low

1423803

SNX1
Sorting nexin-1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025