Interactor 1: IF4E2 (O60573)
Eukaryotic translation initiation factor 4E type 2 (eIF-4E type 2) (eIF4E type 2) (Eukaryotic translation initiation factor 4E homologous protein) (Eukaryotic translation initiation factor 4E-like 3) (eIF4E-like protein 4E-LP) (mRNA cap-binding protein 4EHP) (h4EHP) (mRNA cap-binding protein type 3)
Gene: EIF4E2
Interactor 2: GGYF2 (Q6Y7W6)
GRB10-interacting GYF protein 2 (PERQ amino acid-rich with GYF domain-containing protein 2) (Trinucleotide repeat-containing gene 15 protein)
Gene: GIGYF2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 0.60 | 0.756 |
The method score is based on:
Property | Details |
---|---|
Experiments | 30917308, 22751931, 28514442, 27173435, 24981860, 33961781, 28698298, 33053355 |
Identification Methods | affinity chromatography technology, far western blotting, isothermal titration calorimetry, anti tag coimmunoprecipitation, x ray scattering, pull down, x-ray crystallography |
Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0003723 - RNA binding GO:0005829 - cytosol GO:0017148 - negative regulation of translation GO:0045947 - negative regulation of translational initiation GO:0060339 - negative regulation of type I interferon-mediated signaling pathway and 1 others more... |
Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024