Interactor 1: TLR2 (O60603)
Toll-like receptor 2 (Toll/interleukin-1 receptor-like protein 4) (CD antigen CD282)
Gene: TLR2
Interactor 2: LGR4 (Q9BXB1)
Leucine-rich repeat-containing G-protein coupled receptor 4 (G-protein coupled receptor 48)
Gene: LGR4
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28514442 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_1~LRR_1, LRR_1~LRR_8, LRR_8~LRR_8, LRR_8~LRRNT, LRR_8~LRRCT |
| Common GO terms | GO:0004888 - transmembrane signaling receptor activity GO:0005886 - plasma membrane GO:0045087 - innate immune response |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
