HitPredict

Interactor 1: TSN2 (O60636)
Tetraspanin-2 (Tspan-2) (Tetraspan NET-3)
Gene: TSPAN2

Interactor 2: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Tetraspanin~Tetraspanin
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 228
+	Hs
		602216 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		602239 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		602238 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		237713 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		CD63_HUMAN (1-228): 1.71e-52: 170: 24.49
+	Hs
		279368 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN9_HUMAN (4-224): 3.93e-52: 170: 27.97
+	Hs
		446010 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD63_HUMAN (1-228): 1.71e-52: 170: 24.49
+	Hs
		237719 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		602230 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		887767 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		279369 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		TSN9_HUMAN (4-224): 3.93e-52: 170: 27.97
+	Hs
		602271 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		819445 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		583857 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD53_HUMAN (1-228): 2.26e-47: 157: 26.32
+	Hs
		602222 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		905534 TSN5_HUMAN (8-218): 6.03e-49: 162: 23.44		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		156131 CD9_HUMAN (4-221): 7.4e-52: 169: 46.02		TSN4_HUMAN (4-223): 8.35e-43: 146: 25.53
+	Hs
		111521 CD81_HUMAN (4-218): 4.74e-49: 162: 40.52		K4DIA7_HUMAN (3-203): 4.47e-44: 149: 29.08
+	Hs
		237703 TSN2_HUMAN (1-221): 4.08e-53: 171: 100.00		TSN3_HUMAN (6-226): 2.32e-33: 122: 19.75
+	Hs
		101395 CD81_HUMAN (4-218): 4.74e-49: 162: 40.52		F8VNT9_HUMAN (1-126): 1.6e-14: 69.7: 30.95