HitPredict

Interactor 1: PDE8A (O60658)
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53)
Gene: PDE8A

Interactor 2: NFKB2 (Q00653)
Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
Gene: NFKB2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15596729
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 829 Hs			1 900
+	Hs
		238055 PDE8A_HUMAN (1-829): 0: 1020: 100.00		NFKB1_HUMAN (6-881): 0: 586: 41.27
+	Hs
		238062 PDE8A_HUMAN (1-829): 0: 1020: 100.00		REL_HUMAN (33-456): 2.67e-112: 359: 33.88
+	Hs
		238061 PDE8A_HUMAN (1-829): 0: 1020: 100.00		TF65_HUMAN (24-354): 9.91e-113: 358: 40.96
+	Hs
		238060 PDE8A_HUMAN (1-829): 0: 1020: 100.00		RELB_HUMAN (27-356): 5.22e-89: 296: 39.34
+	Hs
		238056 PDE8A_HUMAN (1-829): 0: 1020: 100.00		IKBA_HUMAN (486-677): 9.26e-26: 110: 39.38
+	Hs
		238065 PDE8A_HUMAN (1-829): 0: 1020: 100.00		IKBB_HUMAN (486-692): 3.79e-20: 95.1: 33.74