Interactor 1: RAD1 (O60671)
Cell cycle checkpoint protein RAD1 (hRAD1) (Rad1-like DNA damage checkpoint protein)
Gene: RAD1

Interactor 2: HUS1 (O60921)
Checkpoint protein HUS1 (hHUS1)
Gene: HUS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.979

The method score is based on:

Property Details
Experiments 26186194, 28514442, 10359610, 10777662, 11340080, 9872989, 11944979, 33961781, 35271311, 15122316, 20847938
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hus1~Rad1
Common GO terms GO:0000077 - DNA damage checkpoint signaling
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006281 - DNA repair
GO:0006974 - DNA damage response
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 282
Hs

1 280
+ Hs
+ Dm
+ Ce
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024