Protein: SSD1
Protein SSD1 (Protein SRK1)

Gene: SSD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 155
UniProt ID: P24276

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0000900 - mRNA regulatory element binding translation repressor activity
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0003730 - mRNA 3'-UTR binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

664245

SSD1
Protein SSD1

2

6

High-throughput

0.811

High

664327

CBK1
Serine/threonine-protein kinase CBK1

5

3

Small-scale

0.720

High

392269

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.640

High

664302

PP4R3
Serine/threonine-protein phosphatase 4 regulatory subunit 3

3

0

Small-scale

0.634

High

523122

HSP71
Heat shock protein SSA1

3

5

High-throughput

0.633

High

664298

ZRG8
Zinc-regulated protein 8

3

0

Small-scale

0.622

High

664248

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.618

High

664263

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

2

2

High-throughput

0.614

High

664322

EIF2A
Eukaryotic translation initiation factor 2A

2

1

High-throughput

0.614

High

664276

SA190
SIT4-associating protein SAP190

2

1

High-throughput

0.612

High

664342

LGE1
Transcriptional regulatory protein LGE1

3

0

High-throughput

0.606

High

602326

PHO85
Cyclin-dependent protein kinase PHO85

2

3

Small-scale

0.602

High

664326

BRE5
UBP3-associated protein BRE5

2

2

High-throughput

0.601

High

664260

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

2

0

Small-scale

0.595

High

664282

PP4R2
Serine/threonine-protein phosphatase 4 regulatory subunit 2

2

0

Small-scale

0.595

High

594206

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

3

Small-scale

0.584

High

664328

PFD4
Prefoldin subunit 4

2

1

High-throughput

0.576

High

578893

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.571

High

401898

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

3

Small-scale

0.561

High

558594

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.559

High

664280

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.554

High

664286

KOG1
Target of rapamycin complex 1 subunit KOG1

1

2

High-throughput

0.552

High

444427

DED1
ATP-dependent RNA helicase DED1

1

3

High-throughput

0.541

High

664246

DBP1
ATP-dependent RNA helicase DBP1

1

3

High-throughput

0.541

High

664249

SRO9
RNA-binding protein SRO9

1

1

High-throughput

0.541

High

664278

PGM2
Phosphoglucomutase 2

1

1

High-throughput

0.541

High

664290

MPT5
Suppressor protein MPT5

1

1

High-throughput

0.541

High

664300

LSM4
LSM complex subunit LSM4

1

1

High-throughput

0.541

High

664309

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.541

High

664359

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.541

High

664258

XPO1
Exportin-1

1

2

High-throughput

0.536

High

664255

CHIT
Endochitinase

1

0

Small-scale

0.529

High

550749

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.518

High

664349

PLM2
Protein PLM2

1

0

High-throughput

0.518

High

664308

SA185
SIT4-associating protein SAP185

1

1

High-throughput

0.515

High

664288

TEM1
Protein TEM1

1

0

High-throughput

0.513

High

364346

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.501

High

441043

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.501

High

642326

MCK1
Protein kinase MCK1

1

1

High-throughput

0.501

High

645875

DBF2
Cell cycle protein kinase DBF2

1

3

High-throughput

0.501

High

646304

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.501

High

656371

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

656698

KC12
Casein kinase I homolog 2

1

1

High-throughput

0.501

High

664261

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

3

High-throughput

0.501

High

664271

TOR1
Serine/threonine-protein kinase TOR1

1

3

High-throughput

0.501

High

664314

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

1

High-throughput

0.501

High

664320

ATG1
Serine/threonine-protein kinase ATG1

1

1

High-throughput

0.501

High

664318

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.493

High

664356

SDO1
Ribosome maturation protein SDO1

1

0

High-throughput

0.493

High

664299

UTP7
U3 small nucleolar RNA-associated protein 7

1

4

High-throughput

0.489

High

664295

LIS1
Nuclear distribution protein PAC1

1

3

High-throughput

0.481

High

664312

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

2

High-throughput

0.481

High

664336

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

1

High-throughput

0.481

High

448644

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

664247

PCL1
PHO85 cyclin-1

1

0

Small-scale

0.480

High

664259

PSK1
Serine/threonine-protein kinase PSK1

1

0

High-throughput

0.480

High

664345

STE20
Serine/threonine-protein kinase STE20

1

0

High-throughput

0.480

High

149601

RS9A
Small ribosomal subunit protein uS4A

1

4

High-throughput

0.479

High

381889

H4
Histone H4

1

2

High-throughput

0.479

High

403363

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

Small-scale

0.479

High

453901

IF4E
Eukaryotic translation initiation factor 4E

1

2

High-throughput

0.479

High

645297

XRN1
5'-3' exoribonuclease 1

1

2

Small-scale

0.479

High

664250

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

1

2

Small-scale

0.479

High

664252

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

664253

RL16A
Large ribosomal subunit protein uL13A

1

3

High-throughput

0.479

High

664256

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

664257

RENT1
ATP-dependent helicase NAM7

1

2

Small-scale

0.479

High

664266

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

664279

GBLP
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.479

High

664289

ITS3
Phosphatidylinositol 4-phosphate 5-kinase MSS4

1

1

High-throughput

0.479

High

664307

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

664315

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

664316

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

664323

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

664324

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

664329

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

664339

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

664340

KIN4
Serine/threonine-protein kinase KIN4

1

2

High-throughput

0.479

High

664348

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

1

High-throughput

0.479

High

664353

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

4

Small-scale

0.479

High

664355

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

664360

CRM2
Homeostatic regulator of DAG

1

1

High-throughput

0.479

High

623773

MYO2
Myosin-2

1

0

Small-scale

0.460

High

632406

CG12
G1/S-specific cyclin CLN2

1

0

Small-scale

0.460

High

664268

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

664297

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

664317

KEL2
Kelch repeat-containing protein 2

1

0

High-throughput

0.460

High

664333

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

664335

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

0

High-throughput

0.460

High

664338

MDM1
Structural protein MDM1

1

0

High-throughput

0.460

High

664344

VPS60
Vacuolar protein-sorting-associated protein 60

1

0

High-throughput

0.460

High

664351

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.460

High

664362

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.460

High

438621

SC160
Protein SCP160

1

0

High-throughput

0.458

High

664251

NOT1
General negative regulator of transcription subunit 1

1

0

Small-scale

0.458

High

664265

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

Small-scale

0.458

High

664267

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

664272

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

664273

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

664274

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

664281

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

664283

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.458

High

664304

TM108
Protein TMA108

1

0

High-throughput

0.458

High

664306

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

664310

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

664319

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

Small-scale

0.458

High

664325

DCP2
m7GpppN-mRNA hydrolase

1

0

Small-scale

0.458

High

664330

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

664331

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.458

High

664332

H3
Histone H3

1

0

High-throughput

0.458

High

664346

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.458

High

664347

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

664350

PAL1
Protein PAL1

1

0

High-throughput

0.458

High

664352

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

664358

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

664287

HAL5
Serine/threonine-protein kinase HAL5

1

1

High-throughput

0.457

High

510221

HSP77
Import motor subunit, mitochondrial

1

4

High-throughput

0.445

High

543884

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.445

High

575894

CYPH
Peptidyl-prolyl cis-trans isomerase

1

1

High-throughput

0.445

High

664254

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.445

High

664262

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

1

High-throughput

0.445

High

664269

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

664284

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

664291

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

664296

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

664301

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

664337

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.445

High

664354

BRE1
E3 ubiquitin-protein ligase BRE1

1

2

High-throughput

0.445

High

664363

YH41A
Transposon Ty4-H Gag polyprotein

1

1

High-throughput

0.439

High

383530

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

409949

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

433462

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.437

High

454893

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.437

High

502864

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.437

High

512835

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

664270

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.437

High

664277

UTH1
Probable secreted beta-glucosidase UTH1

1

1

Small-scale

0.437

High

664305

SIM1
Probable secreted beta-glucosidase SIM1

1

1

Small-scale

0.437

High

664334

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

664343

YMZ2
WD repeat-containing protein YMR102C

1

3

High-throughput

0.437

High

664357

RS10A
Small ribosomal subunit protein eS10A

1

4

High-throughput

0.437

High

664361

DBP10
ATP-dependent RNA helicase DBP10

1

8

High-throughput

0.437

High

590540

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

664264

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

664292

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

664303

6P21
6-phosphofructo-2-kinase 1

1

0

High-throughput

0.426

High

664341

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

664311

STU2
Protein STU2

1

2

High-throughput

0.407

High

664321

PDK2
[Pyruvate dehydrogenase

1

0

High-throughput

0.261

Low

664275

STB6
Protein STB6

1

0

High-throughput

0.251

Low

664313

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

664285

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.249

Low

664293

ATC3
Phospholipid-transporting ATPase DRS2

1

0

Small-scale

0.249

Low

664294

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025