HitPredict

Interactor 1: IMA7 (O60684)
Importin subunit alpha-7 (Karyopherin subunit alpha-6)
Gene: KPNA6

Interactor 2: NOP58 (Q9Y2X3)
Nucleolar protein 58 (Nucleolar protein 5)
Gene: NOP58

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 529
+	Hs
		133254 IMA7_HUMAN (1-536): 7e-160: 467: 100.00		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		853761 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		NOP58_HUMAN (1-529): 0: 602: 100.00
+	Hs
		133234 IMA3_HUMAN (4-536): 9.52e-152: 446: 47.10		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		853524 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		NOP58_HUMAN (1-529): 0: 602: 100.00
+	Hs
		133237 IMA6_HUMAN (1-536): 3.72e-149: 440: 83.67		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		131337 IMA4_HUMAN (4-536): 4.93e-148: 436: 45.98		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Hs
		133392 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		NOP56_HUMAN (1-529): 0: 577: 36.75
+	Sp
		293205 IMA2_SCHPO (11-536): 4.57e-144: 427: 52.26		NOP56_SCHPO (2-441): 0: 538: 38.14
+	Sc
		972944 IMA1_YEAST (2-536): 9e-140: 416: 50.37		NOP56_YEAST (2-430): 2.72e-176: 508: 37.78
+	Sc
		972949 IMA1_YEAST (2-536): 9e-140: 416: 50.37		NOP58_YEAST (2-438): 2.75e-164: 477: 49.55
+	Hs
		853666 IMA5_HUMAN (4-536): 1.39e-146: 433: 80.11		PRP31_HUMAN (154-528): 1.12e-129: 388: 21.83
+	Hs
		853397 IMA1_HUMAN (1-536): 5.59e-142: 421: 44.92		PRP31_HUMAN (154-528): 1.12e-129: 388: 21.83