HitPredict

Interactor 1: CTND1 (O60716)
Catenin delta-1 (Cadherin-associated Src substrate) (CAS) (p120 catenin) (p120(ctn)) (p120(cas))
Gene: CTNND1

Interactor 2: YES (P07947)
Tyrosine-protein kinase Yes (EC 2.7.10.2) (Proto-oncogene c-Yes) (p61-Yes)
Gene: YES1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	12640114, 36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 968 Hs			1 543
+	Hs
		239035 CTND1_HUMAN (1-968): 0: 939: 100.00		SRC_HUMAN (1-543): 0: 601: 74.22
+	Hs
		239024 CTND1_HUMAN (1-968): 0: 939: 100.00		FYN_HUMAN (1-543): 0: 582: 72.16
+	Hs
		239023 CTND1_HUMAN (1-968): 0: 939: 100.00		LCK_HUMAN (83-541): 0: 540: 60.78
+	Hs
		239026 CTND1_HUMAN (1-968): 0: 939: 100.00		LYN_HUMAN (1-541): 3.82e-179: 515: 53.69
+	Hs
		239089 CTND1_HUMAN (1-968): 0: 939: 100.00		BLK_HUMAN (66-538): 5.05e-174: 502: 59.07
+	Hs
		239093 CTND1_HUMAN (1-968): 0: 939: 100.00		EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00
+	Hs
		239072 CTND1_HUMAN (1-968): 0: 939: 100.00		TEC_HUMAN (7-535): 6.76e-156: 460: 32.96
+	Hs
		411837 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		LCK_HUMAN (83-541): 0: 540: 60.78
+	Hs
		433972 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		LYN_HUMAN (1-541): 3.82e-179: 515: 53.69
+	Hs
		522819 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		SRC_HUMAN (1-543): 0: 601: 74.22
+	Hs
		412054 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		FYN_HUMAN (1-543): 0: 582: 72.16
+	Hs
		872698 PKP2_HUMAN (35-867): 2.06e-154: 479: 23.32		EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00
+	Hs
		411579 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		LCK_HUMAN (83-541): 0: 540: 60.78
+	Hs
		433616 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		LYN_HUMAN (1-541): 3.82e-179: 515: 53.69
+	Hs
		433555 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		LYN_HUMAN (1-541): 3.82e-179: 515: 53.69
+	Hs
		337371 CTNB1_HUMAN (156-923): 1.23e-113: 369: 16.81		ABL1_HUMAN (41-543): 5.93e-161: 489: 39.10
+	Hs
		542244 PLAK_HUMAN (169-906): 2.02e-105: 346: 15.85		EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00
+	Hs
		411829 PKP4_HUMAN (8-353): 3.73e-18: 92.4: 16.20		LCK_HUMAN (83-541): 0: 540: 60.78
+	Hs
		433962 PKP4_HUMAN (8-353): 3.73e-18: 92.4: 16.20		LYN_HUMAN (1-541): 3.82e-179: 515: 53.69
+	Hs
		872696 PKP4_HUMAN (8-353): 3.73e-18: 92.4: 16.20		EPHA4_HUMAN (4-542): 2.62e-155: 470: 25.00