HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: PTPRU (Q92729)
Receptor-type tyrosine-protein phosphatase U (R-PTP-U) (EC 3.1.3.48) (Pancreatic carcinoma phosphatase 2) (PCP-2) (Protein-tyrosine phosphatase J) (PTP-J) (hPTP-J) (Protein-tyrosine phosphatase pi) (PTP pi) (Protein-tyrosine phosphatase receptor omicron) (PTP-RO) (Receptor-type protein-tyrosine phosphatase psi) (R-PTP-psi)
Gene: PTPRU

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 1446
+	Hs
		239764 HCN1_HUMAN (1-890): 0: 684: 100.00		PTPRA_HUMAN (673-1443): 0: 755: 28.46
+	Hs
		239785 HCN1_HUMAN (1-890): 0: 684: 100.00		PTPRG_HUMAN (295-1445): 0: 670: 21.71
+	Hs
		239737 HCN1_HUMAN (1-890): 0: 684: 100.00		PTPRF_HUMAN (7-941): 1.88e-67: 254: 11.64
+	Hs
		239784 HCN1_HUMAN (1-890): 0: 684: 100.00		PTPRD_HUMAN (187-963): 3.95e-39: 162: 10.28
+	Hs
		239975 HCN1_HUMAN (1-890): 0: 684: 100.00		PTPRS_HUMAN (187-943): 1.73e-38: 160: 10.32