Protein: KPR5
Ribose-phosphate pyrophosphokinase 5 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 5)

Gene: KPR5, PRS5
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: Q12265

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

792603

KPR4
Ribose-phosphate pyrophosphokinase 4

6

18

Small-scale

0.938

High

800685

KPR2
Ribose-phosphate pyrophosphokinase 2

5

17

Small-scale

0.920

High

746764

KPR1
Ribose-phosphate pyrophosphokinase 1

3

18

Small-scale

0.849

High

1084696

KPR5
Ribose-phosphate pyrophosphokinase 5

3

17

Small-scale

0.847

High

801798

KPR3
Ribose-phosphate pyrophosphokinase 3

2

17

High-throughput

0.793

High

800636

RIM11
Serine/threonine-protein kinase RIM11/MSD1

2

4

Small-scale

0.614

High

528030

HSP72
Heat shock protein SSA2

2

9

High-throughput

0.571

High

546763

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.536

High

1030612

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

850264

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

7

High-throughput

0.533

High

368358

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

2

High-throughput

0.501

High

816503

BUD16
Putative pyridoxal kinase BUD16

1

1

High-throughput

0.501

High

844354

ELP2
Elongator complex protein 2

1

3

High-throughput

0.501

High

919407

RBG2
Ribosome-interacting GTPase 2

1

0

High-throughput

0.493

High

806389

KOG1
Target of rapamycin complex 1 subunit KOG1

1

3

High-throughput

0.481

High

751362

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

0

High-throughput

0.480

High

781127

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.480

High

923068

TR112
Multifunctional methyltransferase subunit TRM112

1

0

High-throughput

0.480

High

518427

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.479

High

580256

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

680165

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

701749

URA7
CTP synthase 1

1

1

High-throughput

0.479

High

727407

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

795598

ATG8
Autophagy-related protein 8

1

1

High-throughput

0.479

High

803721

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

815280

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

922661

HST2
NAD-dependent protein deacetylase HST2

1

2

High-throughput

0.479

High

1059423

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

1084697

DBP10
ATP-dependent RNA helicase DBP10

1

6

High-throughput

0.479

High

1084698

CMR1
DNA damage-binding protein CMR1

1

4

High-throughput

0.479

High

671248

SIS1
Protein SIS1

1

5

High-throughput

0.470

High

1044509

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

531932

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.457

High

821045

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

1

High-throughput

0.457

High

805725

YHS2
MIP18 family protein YHR122W

1

2

High-throughput

0.457

High

481814

HSP73
Heat shock protein SSA3

1

9

High-throughput

0.445

High

525565

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

676469

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.445

High

742688

HSP7F
Heat shock protein homolog SSE1

1

11

High-throughput

0.445

High

752890

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

804563

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

820131

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

755319

NUF2
Kinetochore protein NUF2

1

5

Small-scale

0.439

High

1084645

RLM1
Transcription factor RLM1

1

2

Small-scale

0.439

High

381309

H2B1
Histone H2B.1

1

2

High-throughput

0.437

High

381668

H2B2
Histone H2B.2

1

2

High-throughput

0.437

High

708543

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

795277

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

963794

H3
Histone H3

1

2

High-throughput

0.437

High

1054012

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

1065539

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

912468

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

825839

YRB2
Ran-specific GTPase-activating protein 2

1

0

High-throughput

0.279

Low

865855

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.261

Low

673460

ADH7
NADP-dependent alcohol dehydrogenase 7

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025