HitPredict

Interactor 1: HCN1 (O60741)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1)
Gene: HCN1

Interactor 2: PCDAC (Q9UN75)
Protocadherin alpha-12 (PCDH-alpha-12)
Gene: PCDHA12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 941
+	Hs
		240268 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA4_HUMAN (1-941): 0: 1042: 81.10
+	Hs
		240306 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA2_HUMAN (1-941): 0: 1036: 80.49
+	Hs
		240308 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA1_HUMAN (25-941): 0: 1025: 80.02
+	Hs
		240303 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDG6_HUMAN (1-892): 0: 912: 37.53
+	Hs
		240300 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGL_HUMAN (29-889): 0: 551: 38.81
+	Hs
		240302 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGD_HUMAN (2-447): 1.53e-100: 337: 26.46
+	Hs
		240307 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDAB_HUMAN (2-446): 9.32e-100: 335: 25.76
+	Hs
		240267 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGG_HUMAN (2-447): 7.68e-97: 327: 26.96
+	Hs
		240305 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDA8_HUMAN (2-446): 3.37e-95: 323: 24.19
+	Hs
		240304 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDG3_HUMAN (1-447): 8e-94: 319: 24.19
+	Hs
		240309 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDC2_HUMAN (452-913): 3.55e-46: 181: 15.87
+	Hs
		240297 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDB2_HUMAN (511-908): 7.38e-39: 157: 14.87
+	Hs
		240265 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDB8_HUMAN (456-908): 2.47e-37: 153: 14.86
+	Hs
		240295 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDB5_HUMAN (463-908): 6.93e-37: 151: 14.14
+	Hs
		240301 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDGI_HUMAN (1-234): 2.29e-33: 140: 18.33
+	Hs
		240298 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDBF_HUMAN (615-901): 6.35e-14: 78.1: 10.00
+	Hs
		240203 HCN1_HUMAN (1-890): 0: 684: 100.00		PCDBG_HUMAN (615-901): 5.29e-11: 68.8: 8.56