HitPredict

Interactor 1: CYTIP (O60759)
Cytohesin-interacting protein (Cytohesin binder and regulator) (CYBR) (Cytohesin-associated scaffolding protein) (CASP) (Cytohesin-binding protein HE) (Cbp HE) (Pleckstrin homology Sec7 and coiled-coil domains-binding protein)
Gene: CYTIP

Interactor 2: BLK (P51451)
Tyrosine-protein kinase Blk (EC 2.7.10.2) (B lymphocyte kinase) (p55-Blk)
Gene: BLK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 359 Hs			1 505
+	Hs
		412243 GRASP_HUMAN (40-359): 1.85e-58: 195: 36.64		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		523041 GRASP_HUMAN (40-359): 1.85e-58: 195: 36.64		SRC_HUMAN (1-503): 0: 560: 54.22
+	Hs
		523212 SHAN2_HUMAN (47-300): 5.72e-36: 140: 16.72		SRC_HUMAN (1-503): 0: 560: 54.22
+	Hs
		167061 ARHGB_HUMAN (53-325): 1.11e-34: 137: 15.81		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		442887 GOPC_HUMAN (5-189): 2.02e-31: 125: 16.04		HCK_HUMAN (1-505): 0: 574: 62.92
+	Mm
		411930 DLG1_MOUSE (59-171): 1.93e-17: 85.8: 15.79		LCK_MOUSE (1-505): 0: 577: 59.35
+	Hs
		411755 RHG21_HUMAN (55-271): 9.67e-20: 93: 21.63		LCK_HUMAN (1-505): 0: 569: 59.15
+	Hs
		411698 DLG1_HUMAN (59-171): 9.43e-19: 89.7: 16.67		LCK_HUMAN (1-505): 0: 569: 59.15
+	Hs
		412128 DLG4_HUMAN (28-172): 1.61e-19: 92: 13.70		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		153859 NHRF1_HUMAN (24-233): 3.66e-22: 97.8: 14.75		YES_HUMAN (1-503): 0: 555: 53.15
+	Hs
		412342 SHAN3_HUMAN (76-283): 7.17e-19: 90.3: 20.00		FYN_HUMAN (1-503): 0: 562: 54.75
+	Hs
		523133 SHAN3_HUMAN (76-283): 7.17e-19: 90.3: 20.00		SRC_HUMAN (1-503): 0: 560: 54.22
+	Mm
		403445 DLG4_MOUSE (28-171): 1.47e-19: 92: 13.79		SRC_MOUSE (1-503): 0: 557: 54.51
+	Hs
		411696 PTN13_HUMAN (4-271): 3.27e-15: 79.3: 15.00		LCK_HUMAN (1-505): 0: 569: 59.15
+	Mm
		403435 SHAN3_MOUSE (76-282): 6.84e-18: 87.3: 20.08		SRC_MOUSE (1-503): 0: 557: 54.51
+	Hs
		433814 RHG21_HUMAN (55-271): 9.67e-20: 93: 21.63		LYN_HUMAN (1-505): 0: 551: 59.77
+	Hs
		433731 DLG1_HUMAN (59-171): 9.43e-19: 89.7: 16.67		LYN_HUMAN (1-505): 0: 551: 59.77
+	Hs
		167058 ARHGB_HUMAN (53-325): 1.11e-34: 137: 15.81		ABL1_HUMAN (54-504): 6.77e-163: 492: 41.09
+	Hs
		782836 MAST1_HUMAN (82-343): 2.38e-35: 139: 15.09		CSK_HUMAN (51-495): 1.16e-155: 452: 36.54
+	Hs
		337552 SHAN3_HUMAN (76-283): 7.17e-19: 90.3: 20.00		ABL1_HUMAN (54-504): 6.77e-163: 492: 41.09