HitPredict

Interactor 1: CYTIP (O60759)
Cytohesin-interacting protein (Cytohesin binder and regulator) (CYBR) (Cytohesin-associated scaffolding protein) (CASP) (Cytohesin-binding protein HE) (Cbp HE) (Pleckstrin homology Sec7 and coiled-coil domains-binding protein)
Gene: CYTIP

Interactor 2: SNX27 (Q96L92)
Sorting nexin-27
Gene: SNX27

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17577583
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 541
+	Hs
		1238666 GOPC_HUMAN (5-189): 2.02e-31: 125: 16.04		SNX31_HUMAN (173-541): 1.77e-128: 384: 22.06
+	Hs
		240487 CYTIP_HUMAN (1-359): 5.2e-90: 276: 100.00		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Rn
		1246921 GRASP_RAT (40-359): 7.46e-62: 204: 35.44		GRASP_RAT (7-172): 5.89e-30: 123: 24.86
+	Rn
		291510 GRASP_RAT (40-359): 7.46e-62: 204: 35.44		MAGI2_RAT (45-372): 6.38e-17: 86.5: 14.79
+	Mm
		88368 SHAN1_MOUSE (74-341): 4.5e-51: 185: 19.94		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Hs
		167108 ARHGB_HUMAN (53-325): 1.11e-34: 137: 15.81		NEB2_HUMAN (40-314): 3.95e-34: 139: 17.98
+	Mm
		1163968 SHAN2_MOUSE (76-300): 2.64e-32: 130: 17.63		NEB2_MOUSE (40-314): 1.09e-33: 138: 17.98
+	Hs
		1377934 SHAN1_HUMAN (74-346): 1.91e-33: 133: 19.52		SHAN1_HUMAN (43-169): 7.26e-32: 133: 30.71
+	Hs
		1316321 SHAN1_HUMAN (74-346): 1.91e-33: 133: 19.52		SHAN3_HUMAN (44-148): 1.57e-21: 101: 37.14
+	Hs
		1334777 LIN7B_HUMAN (2-199): 3.57e-32: 121: 22.11		LIN7C_HUMAN (35-136): 1.5e-27: 111: 34.95
+	Mm
		1115992 SHAN2_MOUSE (76-300): 2.64e-32: 130: 17.63		SHAN3_MOUSE (44-148): 2.57e-21: 100: 36.19
+	Rn
		1144361 DLG2_RAT (72-170): 3.84e-20: 93.9: 19.00		SHAN1_RAT (43-183): 5e-32: 133: 30.28
+	Hs
		1075405 NHRF2_HUMAN (55-242): 5.06e-23: 100: 18.42		NHRF2_HUMAN (9-207): 1.8e-24: 106: 21.78
+	Hs
		230903 MAST3_HUMAN (83-333): 1.54e-32: 130: 15.10		MAGI1_HUMAN (2-334): 3.18e-13: 74.9: 17.51
+	Hs
		153922 NHRF2_HUMAN (55-242): 5.06e-23: 100: 18.42		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Hs
		153843 NHRF1_HUMAN (24-233): 3.66e-22: 97.8: 14.75		NHRF1_HUMAN (12-209): 7.91e-23: 101: 22.89
+	Dm
		677711 Q9VBY7_DROME (2-186): 7.31e-32: 120: 17.74		DLG1_DROME (44-160): 1.73e-12: 72.3: 19.49
+	Hs
		1075416 NHRF2_HUMAN (55-242): 5.06e-23: 100: 18.42		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70
+	Hs
		153926 NHRF1_HUMAN (24-233): 3.66e-22: 97.8: 14.75		NHRF3_HUMAN (38-313): 4.98e-16: 82.7: 13.70