HitPredict

Interactor 1: HNRC1 (O60812)
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)
Gene: HNRNPCL1

Interactor 2: RALY (Q9UKM9)
RNA-binding protein Raly (Autoantigen p542) (Heterogeneous nuclear ribonucleoprotein C-like 2) (hnRNP core protein C-like 2) (hnRNP associated with lethal yellow protein homolog)
Gene: RALY

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	32296183, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 306
+	Hs
		241314 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		71273 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		71142 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		432988 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		RALY_HUMAN (1-306): 1.15e-143: 408: 100.00
+	Hs
		432751 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		Q53GL6_HUMAN (1-306): 7.94e-142: 403: 97.72
+	Hs
		241323 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		71163 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		241255 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		241244 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		HNRC1_HUMAN (6-297): 1.05e-98: 293: 43.43
+	Hs
		71043 HNRC1_HUMAN (1-293): 1.3e-98: 293: 100.00		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		71066 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38
+	Hs
		432789 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		RALYL_HUMAN (1-224): 3.08e-105: 310: 64.83
+	Hs
		71024 HNRC2_HUMAN (1-293): 3.5e-94: 281: 96.25		HNRC2_HUMAN (6-218): 4.64e-97: 289: 52.07
+	Hs
		432507 HNRPC_HUMAN (1-293): 1.35e-86: 262: 86.93		HNRPC_HUMAN (6-219): 3.17e-99: 295: 52.38