HitPredict

Interactor 1: H2B1K (O60814)
Histone H2B type 1-K (H2B K) (HIRA-interacting protein 1)
Gene: H2BC12

Interactor 2: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 292
+	Hs
		625471 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39
+	Hs
		625165 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		CDK2_HUMAN (1-292): 2.7e-143: 406: 59.39
+	Hs
		918294 H2B1C_HUMAN (1-126): 1.07e-53: 166: 99.21		CDK5_HUMAN (1-292): 6.09e-139: 395: 100.00
+	Hs
		414779 H2B1B_HUMAN (1-126): 1.52e-53: 165: 96.83		CDK1_HUMAN (1-289): 1.13e-134: 384: 56.01
+	Hs
		841302 H2B1L_HUMAN (1-126): 2.18e-52: 163: 97.62		CDK7_HUMAN (2-292): 2.63e-127: 367: 45.24
+	Hs
		960439 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		CDK17_HUMAN (1-291): 3.52e-121: 358: 55.82
+	Hs
		300639 H2B2E_HUMAN (1-126): 5.55e-54: 166: 98.41		CDK14_HUMAN (4-291): 1.17e-103: 311: 54.61