Interactor 1: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Interactor 2: DKC1 (O60832)
H/ACA ribonucleoprotein complex subunit DKC1 (EC 5.4.99.-) (CBF5 homolog) (Dyskerin) (Nopp140-associated protein of 57 kDa) (Nucleolar protein NAP57) (Nucleolar protein family A member 4) (snoRNP protein DKC1)
Gene: DKC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21931644
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DKCLD~DKCLD, DKCLD~PUA, DKCLD~TruB_C_2, DKCLD~TruB_N, PUA~PUA, PUA~TruB_C_2, PUA~TruB_N, TruB_C_2~TruB_N, TruB_N~TruB_N
Common GO terms GO:0000455 - enzyme-directed rRNA pseudouridine synthesis
GO:0000495 - box H/ACA sno(s)RNA 3'-end processing
GO:0001650 - fibrillar center
GO:0003720 - telomerase activity
GO:0003723 - RNA binding
and 25 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 514
Hs

1 514
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024