HitPredict

Interactor 1: SH21A (O60880)
SH2 domain-containing protein 1A (Duncan disease SH2-protein) (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: SH2D1A

Interactor 2: SLAF6 (Q96DU3)
SLAM family member 6 (Activating NK receptor) (NK-T-B-antigen) (NTB-A) (CD antigen CD352)
Gene: SLAMF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.728

The method score is based on:

Property Details
Experiments 11489943, 19150402, 24688028, 22912825, 16920955, 23346089
Identification Methods affinity chromatography technology, peptide array, anti bait coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0045954 - positive regulation of natural killer cell mediated cytotoxicity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 128
Hs

1 332
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024