HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: BAG5 (Q9UL15)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 0.60 0.624

The method score is based on:

Property Details
Experiments 35509820, 15603737
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
and 4 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 465
Hs

1 447
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025