Protein: BAG4
BAG family molecular chaperone regulator 4 (BAG-4) (Bcl-2-associated athanogene 4) (Silencer of death domains)

Gene: BAG4
Organism: Homo sapiens
Interactions: 236
UniProt ID: O95429

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

336616

HSP7C
Heat shock cognate 71 kDa protein

6

20

Small-scale

0.936

High

336646

HSP72
Heat shock-related 70 kDa protein 2

3

20

High-throughput

0.865

High

336630

HS71L
Heat shock 70 kDa protein 1-like

3

20

High-throughput

0.858

High

336621

HSP76
Heat shock 70 kDa protein 6

3

20

High-throughput

0.852

High

336785

DCP1A
mRNA-decapping enzyme 1A

5

1

High-throughput

0.723

High

336717

DCP1B
mRNA-decapping enzyme 1B

4

1

High-throughput

0.694

High

336686

CC038
Uncharacterized protein C3orf38

4

0

High-throughput

0.669

High

336651

HSF2
Heat shock factor protein 2

3

6

High-throughput

0.667

High

336620

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

1

High-throughput

0.654

High

336780

UNKL
Putative E3 ubiquitin-protein ligase UNKL

3

3

High-throughput

0.654

High

336742

EDC3
Enhancer of mRNA-decapping protein 3

3

0

High-throughput

0.646

High

336793

TBCD7
TBC1 domain family member 7

3

0

High-throughput

0.643

High

336758

DNJC7
DnaJ homolog subfamily C member 7

2

9

High-throughput

0.635

High

273464

DJC13
DnaJ homolog subfamily C member 13

2

20

High-throughput

0.628

High

320811

KLH18
Kelch-like protein 18

2

3

High-throughput

0.628

High

336637

YAP1
Transcriptional coactivator YAP1

2

4

High-throughput

0.628

High

336649

HSF1
Heat shock factor protein 1

2

6

High-throughput

0.628

High

336685

BCORL
BCL-6 corepressor-like protein 1

2

3

High-throughput

0.628

High

336691

ZN318
Zinc finger protein 318

2

1

High-throughput

0.628

High

336615

RU1C
U1 small nuclear ribonucleoprotein C

3

0

High-throughput

0.626

High

336631

HSP74
Heat shock 70 kDa protein 4

1

20

Small-scale

0.618

High

176382

ZBTB5
Zinc finger and BTB domain-containing protein 5

2

2

High-throughput

0.606

High

276402

PDCD6
Programmed cell death protein 6

2

4

High-throughput

0.606

High

336611

FYN
Tyrosine-protein kinase Fyn

2

2

High-throughput

0.606

High

336627

PSB5
Proteasome subunit beta type-5

2

3

High-throughput

0.606

High

336640

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.606

High

336650

RUNX1
Runt-related transcription factor 1

2

2

High-throughput

0.606

High

336654

TLE5
TLE family member 5

2

1

High-throughput

0.606

High

336669

LASP1
LIM and SH3 domain protein 1

2

3

High-throughput

0.606

High

336680

KR134
Keratin-associated protein 13-4

2

1

High-throughput

0.606

High

336683

P5CR3
Pyrroline-5-carboxylate reductase 3

2

1

High-throughput

0.606

High

336694

TBC3G
TBC1 domain family member 3G

2

1

High-throughput

0.606

High

336705

AP2D
Transcription factor AP-2-delta

2

1

High-throughput

0.606

High

336710

DZIP3
E3 ubiquitin-protein ligase DZIP3

2

6

High-throughput

0.606

High

336712

SIAH1
E3 ubiquitin-protein ligase SIAH1

2

1

High-throughput

0.606

High

336724

KCTD6
BTB/POZ domain-containing protein KCTD6

2

4

High-throughput

0.606

High

336728

SH3R2
E3 ubiquitin-protein ligase SH3RF2

2

3

High-throughput

0.606

High

336751

KCTD7
BTB/POZ domain-containing protein KCTD7

2

4

High-throughput

0.606

High

336761

KR412
Keratin-associated protein 4-12

2

3

High-throughput

0.606

High

336767

KRA45
Keratin-associated protein 4-5

2

3

High-throughput

0.606

High

336768

KRA44
Keratin-associated protein 4-4

2

3

High-throughput

0.606

High

336769

KRA42
Keratin-associated protein 4-2

2

3

High-throughput

0.606

High

336775

GO45
Golgin-45

2

1

High-throughput

0.606

High

336784

MYOZ1
Myozenin-1

2

1

High-throughput

0.606

High

336790

ABI2
Abl interactor 2

2

2

High-throughput

0.606

High

336792

ZIM2
Zinc finger imprinted 2

2

1

High-throughput

0.606

High

336796

PEF1
Peflin

2

4

High-throughput

0.606

High

336810

MAGD1
Melanoma-associated antigen D1

2

1

High-throughput

0.606

High

284266

GEMI
Geminin

2

0

High-throughput

0.602

High

336643

BRCA2
Breast cancer type 2 susceptibility protein

2

0

High-throughput

0.602

High

336666

NUCG
Endonuclease G, mitochondrial

2

0

High-throughput

0.602

High

336678

QRIC1
Transcriptional regulator QRICH1

2

0

High-throughput

0.602

High

336739

FWCH2
FLYWCH family member 2

2

0

High-throughput

0.602

High

336779

ZN703
Zinc finger protein 703

2

0

High-throughput

0.602

High

336783

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

3

2

High-throughput

0.597

High

336622

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

3

Small-scale

0.595

High

336725

TNIP2
TNFAIP3-interacting protein 2

2

0

High-throughput

0.585

High

123303

BACH
Cytosolic acyl coenzyme A thioester hydrolase

2

0

High-throughput

0.580

High

181220

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.580

High

216157

MTG8R
Protein CBFA2T2

2

0

High-throughput

0.580

High

273962

CREST
Calcium-responsive transactivator

2

0

High-throughput

0.580

High

295969

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.580

High

334363

SYFM
Phenylalanine--tRNA ligase, mitochondrial

2

0

High-throughput

0.580

High

336609

FRIH
Ferritin heavy chain

2

0

High-throughput

0.580

High

336629

KINH
Kinesin-1 heavy chain

2

0

High-throughput

0.580

High

336636

CASP2
Caspase-2

2

0

High-throughput

0.580

High

336645

IST1
IST1 homolog

2

0

High-throughput

0.580

High

336652

ARI5A
AT-rich interactive domain-containing protein 5A

2

0

High-throughput

0.580

High

336658

GPS2
G protein pathway suppressor 2

2

0

High-throughput

0.580

High

336671

ODFP1
Outer dense fiber protein 1

2

0

High-throughput

0.580

High

336688

PHF19
PHD finger protein 19

2

0

High-throughput

0.580

High

336702

ATOSB
Atos homolog protein B

2

0

High-throughput

0.580

High

336704

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.580

High

336708

MYPOP
Myb-related transcription factor, partner of profilin

2

0

High-throughput

0.580

High

336715

PPIL6
Probable inactive peptidyl-prolyl cis-trans isomerase-like 6

2

0

High-throughput

0.580

High

336716

SAXO1
Stabilizer of axonemal microtubules 1

2

0

High-throughput

0.580

High

336740

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.580

High

336749

TEKT5
Tektin-5

2

0

High-throughput

0.580

High

336759

TS101
Tumor susceptibility gene 101 protein

2

0

High-throughput

0.580

High

336765

RAMAC
RNA guanine-N7 methyltransferase activating subunit

2

0

High-throughput

0.580

High

336804

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

2

0

High-throughput

0.580

High

336805

SMAG1
Protein Smaug homolog 1

2

0

High-throughput

0.580

High

336811

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.580

High

292793

GRAP2
GRB2-related adapter protein 2

1

7

High-throughput

0.560

High

63164

VP37C
Vacuolar protein sorting-associated protein 37C

2

1

High-throughput

0.553

High

336606

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

4

High-throughput

0.553

High

336655

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

1

High-throughput

0.553

High

336703

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

1

High-throughput

0.553

High

336727

MYOZ3
Myozenin-3

2

1

High-throughput

0.553

High

336746

ZBT45
Zinc finger and BTB domain-containing protein 45

2

3

High-throughput

0.553

High

336772

TINAL
Tubulointerstitial nephritis antigen-like

2

2

High-throughput

0.553

High

75606

B3KTT5
cDNA FLJ38698 fis, clone KIDNE2002015, highly similar to HEAT SHOCK 70 kDa PROTEIN 1

1

20

High-throughput

0.553

High

336682

Q53FC7
Heat shock 70 kDa protein 6

1

20

High-throughput

0.553

High

336635

ABEC1
C->U-editing enzyme APOBEC-1

1

0

Small-scale

0.549

High

336605

DIRA3
GTP-binding protein Di-Ras3

1

2

High-throughput

0.541

High

336667

I13R2
Interleukin-13 receptor subunit alpha-2

1

2

High-throughput

0.541

High

336690

BRE1A
E3 ubiquitin-protein ligase BRE1A

1

2

High-throughput

0.541

High

336697

ATAD2
ATPase family AAA domain-containing protein 2

1

3

High-throughput

0.541

High

336731

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

4

High-throughput

0.541

High

336745

PDLI2
PDZ and LIM domain protein 2

1

5

High-throughput

0.541

High

336747

LRAT2
Protein LRATD2

1

1

High-throughput

0.541

High

336756

RSLAB
Ras-like protein family member 10B

1

2

High-throughput

0.541

High

336763

MTA3
Metastasis-associated protein MTA3

1

2

High-throughput

0.541

High

336770

RHBT2
Rho-related BTB domain-containing protein 2

1

3

High-throughput

0.541

High

336774

PRD14
PR domain zinc finger protein 14

1

3

High-throughput

0.541

High

336778

BCAS3
BCAS3 microtubule associated cell migration factor

1

2

High-throughput

0.541

High

336799

ERRFI
ERBB receptor feedback inhibitor 1

1

1

High-throughput

0.541

High

336807

KLK5
Kallikrein-5

1

3

High-throughput

0.541

High

336633

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.536

High

274419

DNJB6
DnaJ homolog subfamily B member 6

1

17

High-throughput

0.536

High

298876

DNJB5
DnaJ homolog subfamily B member 5

1

10

High-throughput

0.536

High

336619

ENPL
Endoplasmin

1

3

High-throughput

0.536

High

336625

DNJB1
DnaJ homolog subfamily B member 1

1

10

High-throughput

0.536

High

336626

DDX6
Probable ATP-dependent RNA helicase DDX6

1

1

High-throughput

0.536

High

336638

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

336647

MLF1
Myeloid leukemia factor 1

1

6

High-throughput

0.536

High

336660

STIM1
Stromal interaction molecule 1

1

1

High-throughput

0.536

High

336661

CUL1
Cullin-1

1

9

High-throughput

0.536

High

336662

CUL2
Cullin-2

1

9

High-throughput

0.536

High

336663

CUL3
Cullin-3

1

9

High-throughput

0.536

High

336664

CUL4A
Cullin-4A

1

9

High-throughput

0.536

High

336675

MLF2
Myeloid leukemia factor 2

1

6

High-throughput

0.536

High

336677

NEDD8
Ubiquitin-like protein NEDD8

1

1

High-throughput

0.536

High

336696

EDC4
Enhancer of mRNA-decapping protein 4

1

3

High-throughput

0.536

High

336730

DNJC9
DnaJ homolog subfamily C member 9

1

20

High-throughput

0.536

High

336734

CUL5
Cullin-5

1

9

High-throughput

0.536

High

336752

RBM14
RNA-binding protein 14

1

3

High-throughput

0.536

High

336757

MINT
Msx2-interacting protein

1

4

High-throughput

0.536

High

336777

WNK1
Serine/threonine-protein kinase WNK1

1

3

High-throughput

0.536

High

336786

C1QR1
Complement component C1q receptor

1

2

High-throughput

0.536

High

336789

DJB12
DnaJ homolog subfamily B member 12

1

13

High-throughput

0.536

High

336803

CHIP
E3 ubiquitin-protein ligase CHIP

1

6

High-throughput

0.536

High

332608

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.518

High

336617

ARY2
Arylamine N-acetyltransferase 2

1

0

High-throughput

0.518

High

336618

CCL5
C-C motif chemokine 5

1

0

High-throughput

0.518

High

336707

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.518

High

336732

THRSP
Thyroid hormone-inducible hepatic protein

1

0

High-throughput

0.518

High

336782

BEX1
Protein BEX1

1

0

High-throughput

0.518

High

336795

MRC2
C-type mannose receptor 2

1

0

High-throughput

0.518

High

69886

A8KA13
B-cell CLL/lymphoma 6 member B protein

1

2

High-throughput

0.515

High

336738

Q96BE0
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.514

High

336604

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.513

High

336628

NMT1
Glycylpeptide N-tetradecanoyltransferase 1

1

0

High-throughput

0.513

High

336656

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.513

High

336709

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

336733

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.513

High

336743

DCNL1
DCN1-like protein 1

1

0

High-throughput

0.513

High

336642

KLK7
Kallikrein-7

1

3

High-throughput

0.494

High

336801

KLK9
Kallikrein-9

1

3

High-throughput

0.494

High

336679

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

211247

RFOX2
RNA binding protein fox-1 homolog 2

1

4

High-throughput

0.481

High

336613

VIME
Vimentin

1

6

High-throughput

0.481

High

336614

SNRPA
U1 small nuclear ribonucleoprotein A

1

4

High-throughput

0.481

High

336648

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

1

High-throughput

0.481

High

336659

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.481

High

336672

K1H1
Keratin, type I cuticular Ha1

1

2

High-throughput

0.481

High

336673

SF3B4
Splicing factor 3B subunit 4

1

4

High-throughput

0.481

High

336674

SF01
Splicing factor 1

1

2

High-throughput

0.481

High

336687

PRC2B
Protein PRRC2B

1

2

High-throughput

0.481

High

336711

KR131
Keratin-associated protein 13-1

1

1

High-throughput

0.481

High

336713

ANKH1
Ankyrin repeat and KH domain-containing protein 1

1

2

High-throughput

0.481

High

336721

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.481

High

336753

QKI
KH domain-containing RNA-binding protein QKI

1

2

High-throughput

0.481

High

336760

PKP2
Plakophilin-2

1

1

High-throughput

0.481

High

336764

RBM42
RNA-binding protein 42

1

1

High-throughput

0.481

High

336788

RBM22
Pre-mRNA-splicing factor RBM22

1

3

High-throughput

0.481

High

336791

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.481

High

336808

GRIP1
Glutamate receptor-interacting protein 1

1

2

High-throughput

0.481

High

336809

RBM7
RNA-binding protein 7

1

5

High-throughput

0.481

High

168795

PLD2
Phospholipase D2

1

2

High-throughput

0.479

High

207940

TET3
Methylcytosine dioxygenase TET3

1

1

High-throughput

0.479

High

314982

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

334955

ARI2
E3 ubiquitin-protein ligase ARIH2

1

2

High-throughput

0.479

High

336608

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

336612

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.479

High

336623

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

2

Small-scale

0.479

High

336634

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

336641

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.479

High

336653

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

5

Small-scale

0.479

High

336689

RC3H1
Roquin-1

1

2

High-throughput

0.479

High

336693

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

336698

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

336723

ZBT38
Zinc finger and BTB domain-containing protein 38

1

2

Small-scale

0.479

High

336735

TNR25
Tumor necrosis factor receptor superfamily member 25

1

4

Small-scale

0.479

High

336766

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

1

High-throughput

0.479

High

336771

TRI31
E3 ubiquitin-protein ligase TRIM31

1

5

High-throughput

0.479

High

336781

RC3H2
Roquin-2

1

4

High-throughput

0.479

High

336798

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

336800

FBW1B
F-box/WD repeat-containing protein 11

1

3

High-throughput

0.479

High

336701

Q7KZS0
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.470

High

336741

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.470

High

321395

PRP6
Pre-mRNA-processing factor 6

1

0

High-throughput

0.460

High

336668

BMS1
Ribosome biogenesis protein BMS1 homolog

1

0

High-throughput

0.460

High

336681

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.460

High

336736

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.460

High

336750

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

0

High-throughput

0.460

High

336787

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.460

High

336794

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.460

High

131643

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

Small-scale

0.458

High

336624

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.458

High

336632

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

336676

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.458

High

336684

Q5C8S5
Estrogen receptor alpha mamillary body 1 isoform

1

0

High-throughput

0.458

High

336719

RHG18
Rho GTPase-activating protein 18

1

0

High-throughput

0.458

High

336722

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.458

High

336726

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

336748

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

336802

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

327709

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

2

High-throughput

0.445

High

336610

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.445

High

336639

EAA4
Excitatory amino acid transporter 4

1

1

High-throughput

0.445

High

336670

SL9A5
Sodium/hydrogen exchanger 5

1

8

High-throughput

0.445

High

336692

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.445

High

336700

NBEL2
Neurobeachin-like protein 2

1

3

High-throughput

0.445

High

336762

ZNT2
Proton-coupled zinc antiporter SLC30A2

1

3

High-throughput

0.445

High

336773

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

2

High-throughput

0.445

High

336776

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

2

High-throughput

0.445

High

336797

SL9A2
Sodium/hydrogen exchanger 2

1

8

High-throughput

0.445

High

336806

S27A5
Long-chain fatty acid transport protein 5

1

4

High-throughput

0.445

High

336718

BCL6B
B-cell CLL/lymphoma 6 member B protein

1

2

High-throughput

0.439

High

336665

SIM2
Single-minded homolog 2

1

2

High-throughput

0.437

High

336720

FBXL6
F-box/LRR-repeat protein 6

1

2

High-throughput

0.437

High

336755

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

336695

ZNT6
Zinc transporter 6

1

3

High-throughput

0.407

High

71504

MEI4
Meiosis-specific protein MEI4

2

0

High-throughput

0.316

High

336607

TCL1B
T-cell leukemia/lymphoma protein 1B

2

0

High-throughput

0.316

High

336644

SUOX
Sulfite oxidase, mitochondrial

2

0

High-throughput

0.316

High

336699

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

336714

CMA1C
Protein CIMAP1C

2

0

High-throughput

0.316

High

336729

F222B
Protein FAM222B

2

0

High-throughput

0.316

High

322122

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.282

High

336657

IL24
Interleukin-24

1

0

High-throughput

0.282

High

336706

ITIH5
Inter-alpha-trypsin inhibitor heavy chain H5

1

0

High-throughput

0.282

High

336744

ESIP1
Epithelial-stromal interaction protein 1

1

0

High-throughput

0.282

High

336754

SG3A1
Secretoglobin family 3A member 1

1

0

High-throughput

0.282

High

336737

Q96A10
Endogenous retrovirus group K3 member 1

1

0

High-throughput

0.268

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025