HitPredict

Interactor 1: DNJA2 (O60884)
DnaJ homolog subfamily A member 2 (Cell cycle progression restoration gene 3 protein) (Dnj3) (Dj3) (HIRA-interacting protein 4) (Renal carcinoma antigen NY-REN-14)
Gene: DNAJA2

Interactor 2: ARAF (P10398)
Serine/threonine-protein kinase A-Raf (EC 2.7.11.1) (Proto-oncogene A-Raf) (Proto-oncogene A-Raf-1) (Proto-oncogene Pks)
Gene: ARAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	25852190, 29777862
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 412 Hs			1 606
+	Hs
		488587 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		ARAF_HUMAN (1-606): 0: 579: 100.00
+	Hs
		243247 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		RAF1_HUMAN (13-606): 0: 534: 60.53
+	Hs
		542825 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		BRAF_HUMAN (3-604): 0: 546: 56.68
+	Mm
		655942 DNJA1_MOUSE (4-410): 6.52e-154: 442: 54.52		BRAF_MOUSE (3-604): 0: 542: 55.81
+	Hs
		373768 DNJA1_HUMAN (4-410): 9.87e-155: 444: 54.77		RAF1_HUMAN (13-606): 0: 534: 60.53
+	Hs
		542930 DJB11_HUMAN (2-355): 1.66e-108: 325: 35.85		BRAF_HUMAN (3-604): 0: 546: 56.68
+	Hs
		243486 DNJA2_HUMAN (1-412): 1.22e-168: 480: 100.00		KSR1_HUMAN (50-606): 7.14e-122: 384: 24.24
+	Mm
		655978 DJB11_MOUSE (4-339): 1.77e-54: 186: 37.76		BRAF_MOUSE (3-604): 0: 542: 55.81
+	Dm
		507759 DJSHV_DROME (5-347): 2.37e-53: 182: 36.71		KRAF1_DROME (5-605): 2.05e-167: 496: 42.18
+	Dm
		1096621 Q9VFV9_DROME (4-408): 3.25e-132: 387: 47.90		Q24171_DROME (194-584): 1.1e-49: 187: 33.10
+	Hs
		412302 DNJA3_HUMAN (2-395): 9.05e-116: 348: 26.72		FYN_HUMAN (303-568): 1.51e-37: 148: 33.46