HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	31239290, 32416067, 35987950
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 808
+	Hs
		244116 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MCM2_HUMAN (10-721): 0: 707: 30.62
+	Hs
		244436 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MCM6_HUMAN (2-800): 0: 688: 26.50
+	Hs
		244013 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MCM5_HUMAN (9-713): 0: 685: 28.92
+	Hs
		244012 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MCM4_HUMAN (9-739): 0: 661: 28.03
+	Hs
		244014 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MCM7_HUMAN (10-669): 0: 650: 31.62
+	Hs
		832510 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		MCM2_HUMAN (10-721): 0: 707: 30.62
+	Sc
		667624 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		MCM2_YEAST (6-668): 0: 664: 32.15
+	Sp
		772836 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		MCM2_SCHPO (1-668): 0: 674: 32.31