Protein: KLHL9
Kelch-like protein 9

Gene: KLHL9
Organism: Homo sapiens
Interactions: 90
UniProt ID: Q9P2J3

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0030496 - midbody
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0032465 - regulation of cytokinesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114520

CUL3
Cullin-3

14

20

Small-scale

0.979

High

1454622

KLH13
Kelch-like protein 13

9

19

Small-scale

0.967

High

1199733

KLH22
Kelch-like protein 22

5

19

Small-scale

0.916

High

1454625

KLH21
Kelch-like protein 21

4

19

Small-scale

0.875

High

1386475

KLH29
Kelch-like protein 29

3

19

High-throughput

0.839

High

1454623

FXL17
F-box/LRR-repeat protein 17

3

13

High-throughput

0.839

High

161309

ENC1
Ectoderm-neural cortex protein 1

3

19

High-throughput

0.830

High

1247813

KLH24
Kelch-like protein 24

3

19

High-throughput

0.830

High

1454628

IPP
Actin-binding protein IPP

2

19

High-throughput

0.776

High

1200018

KLH26
Kelch-like protein 26

2

18

High-throughput

0.694

High

1094432

CSN1
COP9 signalosome complex subunit 1

1

17

High-throughput

0.691

High

1115110

CUL4A
Cullin-4A

1

20

High-throughput

0.691

High

1154945

NEDD8
Ubiquitin-like protein NEDD8

1

4

High-throughput

0.691

High

1419357

BACH2
Transcription regulator protein BACH2

1

20

High-throughput

0.691

High

1452113

KLH28
Kelch-like protein 28

1

19

High-throughput

0.691

High

1454578

KLH14
Kelch-like protein 14

1

19

High-throughput

0.691

High

1454624

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

3

13

Small-scale

0.667

High

1391822

AURKB
Aurora kinase B

2

7

Small-scale

0.664

High

1272581

CSN6
COP9 signalosome complex subunit 6

2

12

High-throughput

0.628

High

1370426

CSN5
COP9 signalosome complex subunit 5

2

13

High-throughput

0.628

High

1454626

KLH20
Kelch-like protein 20

1

19

Small-scale

0.621

High

1308603

NUDC3
NudC domain-containing protein 3

3

20

High-throughput

0.604

High

1199045

KLH12
Kelch-like protein 12

1

19

High-throughput

0.575

High

1430056

KLH25
Kelch-like protein 25

1

20

High-throughput

0.575

High

943326

RBM11
Splicing regulator RBM11

2

2

High-throughput

0.549

High

1358033

TM171
Transmembrane protein 171

2

1

High-throughput

0.549

High

167660

GIPC1
PDZ domain-containing protein GIPC1

1

2

High-throughput

0.536

High

563074

MYH8
Myosin-8

1

2

High-throughput

0.536

High

762095

MPI
Mannose-6-phosphate isomerase

1

1

High-throughput

0.536

High

833030

ETV6
Transcription factor ETV6

1

4

High-throughput

0.536

High

1357773

TRI41
E3 ubiquitin-protein ligase TRIM41

1

2

High-throughput

0.536

High

1391966

DCNL1
DCN1-like protein 1

1

10

High-throughput

0.536

High

1398177

HEXI2
Protein HEXIM2

1

3

High-throughput

0.536

High

1446575

NXT2
NTF2-related export protein 2

1

1

High-throughput

0.536

High

772525

IRS1
Insulin receptor substrate 1

1

6

Small-scale

0.515

High

378789

LV657
Immunoglobulin lambda variable 6-57

1

4

High-throughput

0.514

High

1106730

SMAD4
Mothers against decapentaplegic homolog 4

1

2

High-throughput

0.506

High

906807

UB2D1
Ubiquitin-conjugating enzyme E2 D1

1

5

Small-scale

0.501

High

253911

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

325143

HEXI1
Protein HEXIM1

1

3

High-throughput

0.489

High

331527

SPDEF
SAM pointed domain-containing Ets transcription factor

1

5

High-throughput

0.489

High

342682

LY86
Lymphocyte antigen 86

1

1

High-throughput

0.489

High

377318

VIP
VIP peptides [Cleaved into: Intestinal peptide PHV-42

1

1

High-throughput

0.489

High

556964

MYH7
Myosin-7

1

2

High-throughput

0.489

High

574063

HXB1
Homeobox protein Hox-B1

1

3

High-throughput

0.489

High

651608

IBP4
Insulin-like growth factor-binding protein 4

1

4

High-throughput

0.489

High

652682

GNLY
Granulysin

1

1

High-throughput

0.489

High

776140

SOX5
Transcription factor SOX-5

1

7

High-throughput

0.489

High

942166

WNT3A
Protein Wnt-3a

1

3

High-throughput

0.489

High

1099641

NOGG
Noggin

1

1

High-throughput

0.489

High

1122366

SCRIB
Protein scribble homolog

1

4

High-throughput

0.489

High

1152779

KISS1
Metastasis-suppressor KiSS-1

1

3

High-throughput

0.489

High

1179780

TMM44
Transmembrane protein 44

1

1

High-throughput

0.489

High

1220494

F219B
Protein FAM219B

1

3

High-throughput

0.489

High

1248530

KIRR2
Kin of IRRE-like protein 2

1

5

High-throughput

0.489

High

1322365

ZN444
Zinc finger protein 444

1

6

High-throughput

0.489

High

1336963

BHE23
Class E basic helix-loop-helix protein 23

1

3

High-throughput

0.489

High

1340972

MCFD2
Multiple coagulation factor deficiency protein 2

1

1

High-throughput

0.489

High

1347303

FIBIN
Fin bud initiation factor homolog

1

1

High-throughput

0.489

High

1356253

MZB1
Marginal zone B- and B1-cell-specific protein

1

3

High-throughput

0.489

High

1394354

ZN414
Zinc finger protein 414

1

2

High-throughput

0.489

High

1410799

SYT3
Synaptotagmin-3

1

2

High-throughput

0.489

High

1416837

C1QT3
Complement C1q tumor necrosis factor-related protein 3

1

7

High-throughput

0.489

High

1454630

PCDG5
Protocadherin gamma-A5

1

9

High-throughput

0.489

High

1454631

CXA3
Gap junction alpha-3 protein

1

1

High-throughput

0.489

High

920328

PLK1
Serine/threonine-protein kinase PLK1

1

4

Small-scale

0.479

High

957534

UBC12
NEDD8-conjugating enzyme Ubc12

1

15

High-throughput

0.479

High

984000

RBX1
E3 ubiquitin-protein ligase RBX1

1

8

Small-scale

0.479

High

1108237

SQSTM
Sequestosome-1

1

6

High-throughput

0.479

High

1140973

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

1211016

CE170
Centrosomal protein of 170 kDa

1

5

High-throughput

0.479

High

1350480

BICD2
Protein bicaudal D homolog 2

1

4

High-throughput

0.479

High

1397512

CI072
Guanine nucleotide exchange factor C9orf72

1

2

High-throughput

0.479

High

1417076

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

8

High-throughput

0.479

High

1454627

ARI1
E3 ubiquitin-protein ligase ARIH1

1

14

High-throughput

0.479

High

1448513

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

1105183

U119A
Protein unc-119 homolog A

1

1

High-throughput

0.445

High

1310486

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

607178

CEBPB
CCAAT/enhancer-binding protein beta

1

1

Small-scale

0.437

High

887474

CEBPD
CCAAT/enhancer-binding protein delta

1

1

Small-scale

0.437

High

191412

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.426

High

167466

WNT9A
Protein Wnt-9a

1

3

High-throughput

0.407

High

484233

PGFRB
Platelet-derived growth factor receptor beta

1

5

High-throughput

0.407

High

506039

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

1

2

High-throughput

0.407

High

1232141

VASN
Vasorin

1

1

High-throughput

0.407

High

1394687

KIRR1
Kin of IRRE-like protein 1

1

5

High-throughput

0.407

High

1454629

PCDGH
Protocadherin gamma-B5

1

9

High-throughput

0.407

High

1116949

AT1A4
Sodium/potassium-transporting ATPase subunit alpha-4

1

0

High-throughput

0.279

Low

1195338

TPRN
Taperin

1

0

High-throughput

0.279

Low

1334368

IN80E
INO80 complex subunit E

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025