HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: RFC4 (P35249)
Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)
Gene: RFC4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	12192049, 31753913, 32416067, 24981860, 30554943
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 363
+	Hs
		244022 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RFC2_HUMAN (1-358): 8.75e-87: 267: 33.80
+	Hs
		244054 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RFC5_HUMAN (28-356): 5.29e-81: 252: 36.67
+	Hs
		244055 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RFC3_HUMAN (39-361): 1.07e-66: 216: 24.28
+	Hs
		631359 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RFC4_HUMAN (1-363): 7.79e-107: 319: 100.00
+	Hs
		721991 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RFC4_HUMAN (1-363): 7.79e-107: 319: 100.00
+	Hs
		631360 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RFC2_HUMAN (1-358): 8.75e-87: 267: 33.80
+	Hs
		722114 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RFC2_HUMAN (1-358): 8.75e-87: 267: 33.80
+	Hs
		631367 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RFC5_HUMAN (28-356): 5.29e-81: 252: 36.67
+	Hs
		777865 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RFC5_HUMAN (28-356): 5.29e-81: 252: 36.67
+	Hs
		631368 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RFC3_HUMAN (39-361): 1.07e-66: 216: 24.28