HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: AFF1 (P51825)
AF4/FMR2 family member 1 (ALL1-fused gene from chromosome 4 protein) (Protein AF-4) (Protein FEL) (Proto-oncogene AF4)
Gene: AFF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	21030982, 24367103
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1210
+	Hs
		244571 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27
+	Hs
		244438 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79
+	Hs
		244681 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		THOC2_HUMAN (560-916): 5.62e-09: 62.8: 15.61
+	Hs
		1067006 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NIPBL_HUMAN (12-1005): 1.12e-50: 199: 12.27
+	Hs
		631425 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79
+	Hs
		1056838 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		MDC1_HUMAN (161-949): 1.95e-10: 67.6: 10.79
+	Hs
		1067060 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		THOC2_HUMAN (560-916): 5.62e-09: 62.8: 15.61
+	Mm
		101467 KAT2B_MOUSE (327-456): 1.05e-21: 104: 26.92		F8VPR5_MOUSE (72-770): 3.98e-28: 125: 11.92
+	Mm
		1207212 KMT2C_MOUSE (495-1183): 4.41e-22: 106: 13.55		NCOA6_MOUSE (50-1088): 1.15e-11: 71.6: 9.93
+	Dm
		113976 M9PB30_DROME (168-975): 2.55e-17: 90.9: 12.03		M9PB30_DROME (27-449): 7.87e-09: 62.8: 10.82