HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: COPA (P53621)
Coatomer subunit alpha (Alpha-coat protein) (Alpha-COP) (HEP-COP) (HEPCOP) [Cleaved into: Xenin (Xenopsin-related peptide); Proxenin]
Gene: COPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	31239290, 32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 1224
+	Sc
		863629 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		COPA_YEAST (1-1218): 0: 967: 42.71
+	Hs
		245095 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR3_HUMAN (427-714): 2.55e-18: 93.2: 14.15
+	Hs
		244027 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		COPB2_HUMAN (481-644): 1.35e-13: 77.8: 10.53
+	Hs
		244210 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR5_HUMAN (520-631): 6.51e-11: 67.4: 10.35
+	Sp
		252179 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		NLE1_SCHPO (126-509): 3.56e-40: 158: 15.69
+	Dm
		1358857 Q9VTZ1_DROME (336-457): 5.41e-22: 105: 30.89		WDS_DROME (407-617): 3.01e-43: 163: 11.01
+	Sc
		784417 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		COPB2_YEAST (2-272): 3.07e-17: 89.7: 12.28
+	Mm
		903669 KMT2C_MOUSE (495-1183): 4.41e-22: 106: 13.55		WDR5_MOUSE (520-631): 6.51e-11: 67.4: 10.35
+	Hs
		903409 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		WDR5_HUMAN (520-631): 6.51e-11: 67.4: 10.35
+	Hs
		903408 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		WDR5_HUMAN (520-631): 6.51e-11: 67.4: 10.35