HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32416067
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 152
+	Hs
		244239 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58
+	Hs
		244756 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2E3_HUMAN (1-149): 3.17e-75: 224: 44.97
+	Hs
		244147 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UB2E1_HUMAN (1-149): 1.93e-73: 219: 45.64
+	Hs
		244107 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46
+	Hs
		244973 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		UBE2T_HUMAN (7-148): 1.12e-38: 131: 45.89
+	Hs
		849391 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D1_HUMAN (4-149): 3.22e-80: 235: 45.21
+	Hs
		919805 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58
+	Hs
		895863 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89