HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 680
+	Hs
		245097 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08
+	Hs
		245058 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		KDM5B_HUMAN (147-656): 5.55e-61: 224: 13.90
+	Hs
		244060 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75
+	Hs
		244447 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		244356 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		243764 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		NSD2_HUMAN (77-547): 1.68e-36: 149: 11.77
+	Hs
		244960 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SP110_HUMAN (88-587): 6.64e-37: 149: 11.64
+	Hs
		244826 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		RSF1_HUMAN (156-578): 3.04e-34: 142: 16.59
+	Hs
		170259 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56
+	Hs
		631624 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71
+	Hs
		631426 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		1059625 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		631414 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Hs
		331723 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		NSD2_HUMAN (77-547): 1.68e-36: 149: 11.77
+	Hs
		331815 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		NSD2_HUMAN (77-547): 1.68e-36: 149: 11.77
+	Hs
		631557 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		RSF1_HUMAN (156-578): 3.04e-34: 142: 16.59
+	Hs
		1067107 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		RSF1_HUMAN (156-578): 3.04e-34: 142: 16.59
+	Hs
		319198 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04
+	Hs
		319179 BRD1_HUMAN (197-781): 8.89e-33: 140: 13.99		CHD3_HUMAN (298-617): 4.98e-41: 163: 15.21
+	Sc
		975964 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		RCO1_YEAST (427-535): 8.13e-24: 108: 27.03