HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32416067, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1362 Hs			1 432
+	Hs
		244767 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		244210 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		243688 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TBL1X_HUMAN (3-110): 1.72e-27: 116: 13.76
+	Hs
		244901 BRD4_HUMAN (1-1362): 1.08e-121: 414: 100.00		TBL1R_HUMAN (5-110): 6.4e-27: 114: 14.02
+	Hs
		631541 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		FBXW7_HUMAN (66-406): 4.11e-66: 225: 18.26
+	Mm
		903669 KMT2C_MOUSE (495-1183): 4.41e-22: 106: 13.55		WDR5_MOUSE (152-432): 8.2e-55: 186: 14.75
+	Hs
		903409 KAT2B_HUMAN (327-456): 5.61e-22: 105: 26.92		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		903408 KAT2A_HUMAN (327-456): 1.76e-20: 100: 26.15		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		631433 BRD2_HUMAN (3-737): 2.87e-55: 209: 46.43		TAF5_HUMAN (9-141): 3.19e-12: 70.5: 15.19
+	Hs
		1066968 BRD3_HUMAN (37-738): 5.99e-55: 207: 47.53		TAF5_HUMAN (9-141): 3.19e-12: 70.5: 15.19
+	Sc
		744679 GCN5_YEAST (140-462): 1.42e-41: 161: 16.37		TAF5_YEAST (6-140): 1.14e-24: 108: 11.86
+	Dm
		1358857 Q9VTZ1_DROME (336-457): 5.41e-22: 105: 30.89		WDS_DROME (205-432): 3.67e-44: 159: 12.17
+	Sp
		252179 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		NLE1_SCHPO (249-410): 9.85e-25: 107: 12.63
+	Sp
		140404 GCN5_SCHPO (143-461): 4.74e-40: 157: 14.11		TAF5_SCHPO (8-108): 2.05e-14: 77.1: 15.69
+	Sc
		715320 SPT7_YEAST (223-610): 3.64e-27: 122: 12.08		TAF5_YEAST (6-140): 1.14e-24: 108: 11.86
+	Sp
		140401 YK82_SCHPO (49-215): 1.43e-35: 147: 26.35		TAF5_SCHPO (8-108): 2.05e-14: 77.1: 15.69
+	Sp
		140398 SPT7_SCHPO (128-688): 6.38e-25: 114: 12.35		TAF5_SCHPO (8-108): 2.05e-14: 77.1: 15.69
+	Hs
		1074790 BRDT_HUMAN (26-339): 2.9e-26: 119: 19.24		TAF5_HUMAN (9-141): 3.19e-12: 70.5: 15.19
+	Hs
		1017404 PB1_HUMAN (26-956): 2.35e-19: 97.1: 10.81		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52
+	Hs
		1074799 PHIP_HUMAN (26-669): 5.56e-18: 92.9: 13.30		TAF5_HUMAN (9-141): 3.19e-12: 70.5: 15.19