Interactor 1: MCE1 (O60942)
mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]
Gene: RNGTT

Interactor 2: MCE1 (O60942)
mRNA-capping enzyme (HCAP1) (HCE) [Includes: mRNA 5'-triphosphate monophosphatase (EC 3.6.1.74) (mRNA 5'-phosphatase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)]
Gene: RNGTT

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 27432908
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DSPc~DSPc, mRNA_cap_C~mRNA_cap_C, mRNA_cap_C~mRNA_cap_enzyme, mRNA_cap_enzyme~mRNA_cap_enzyme
Common GO terms GO:0004484 - mRNA guanylyltransferase activity
GO:0004651 - polynucleotide 5'-phosphatase activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005634 - nucleus
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 597
Hs

1 597
+ Hs
+ Hs
+ Ca
+ Hs
+ Hs
+ Sc
+ Sp
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024