Interactor 1: EGL1 (O61667)
Programmed cell death activator egl-1 (Egg-laying defective protein 1)
Gene: egl-1
Interactor 2: CED9 (P41958)
Apoptosis regulator ced-9 (Cell death protein 9)
Gene: ced-9
Species: Caenorhabditis elegans
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.934 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9604928, 15605074, 12894216, 11027303, 19855391, 16208361, 9837929, 19414600, 10846174, 15383288, 16735440, 16167070, 17011494 |
| Identification Methods | biochemical, two hybrid, pull down, affinity chromatography technology, x-ray crystallography, enzymatic study, anti tag coimmunoprecipitation |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~EGL-1 |
| Common GO terms | GO:0005739 - mitochondrion GO:0006915 - apoptotic process GO:0030042 - actin filament depolymerization GO:0043065 - positive regulation of apoptotic process GO:0050829 - defense response to Gram-negative bacterium and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
