HitPredict

Interactor 1: CYCL (O61734)
Protein cycle (Brain and muscle ARNT-like 1) (BMAL1) (MOP3)
Gene: cyc

Interactor 2: CLOCK (O61735)
Circadian locomoter output cycles protein kaput (dCLOCK) (dPAS1)
Gene: Clk

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 10409723, 17635913, 19376119, 23935523, 9616122, 10417378, 23847101, 27489346, 28973907, 25121504, 30995488, unassigned4
Identification Methods affinity chromatography technology, two hybrid, pull down, miniaturized immunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH, HLH~PAS, PAS~PAS_11, PAS_11~PAS_11
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003053 - circadian regulation of heart rate
GO:0003677 - DNA binding
GO:0005634 - nucleus
and 13 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Last updated: 15 Jul 2024