Interactor 1: PLXC1 (O60486)
Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232)
Gene: PLXNC1
Interactor 2: SEM7A (O75326)
Semaphorin-7A (CDw108) (JMH blood group antigen) (John-Milton-Hargen human blood group Ag) (Semaphorin-K1) (Sema K1) (Semaphorin-L) (Sema L) (CD antigen CD108)
Gene: SEMA7A
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20727575 |
| Identification Methods | isothermal titration calorimetry, x-ray crystallography |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ig_2~PSI, PSI~PSI, PSI~Sema, PSI~TIG, Sema~TIG |
| Common GO terms | GO:0005886 - plasma membrane GO:0016020 - membrane GO:0071526 - semaphorin-plexin signaling pathway |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
