Protein: SEM3C
Semaphorin-3C (Semaphorin-E) (Sema E)

Gene: SEM3C, SEMA3C
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q99985

Gene Ontology (top 5):
GO:0001755 - neural crest cell migration
GO:0001756 - somitogenesis
GO:0001974 - blood vessel remodeling
GO:0003148 - outflow tract septum morphogenesis
GO:0003215 - cardiac right ventricle morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1101407

SG2A2
Mammaglobin-A

2

2

High-throughput

0.811

High

325232

SEM3D
Semaphorin-3D

1

15

High-throughput

0.691

High

593479

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.691

High

1100656

SEM3F
Semaphorin-3F

1

12

High-throughput

0.691

High

1128173

SEM3A
Semaphorin-3A

1

15

High-throughput

0.691

High

1295027

TMM25
Transmembrane protein 25

1

2

High-throughput

0.691

High

1408458

SIRPD
Signal-regulatory protein delta

1

1

High-throughput

0.691

High

1408467

ST14
Suppressor of tumorigenicity 14 protein

1

4

High-throughput

0.691

High

760494

SDC2
Syndecan-2

3

1

High-throughput

0.662

High

377701

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.656

High

774578

BASI
Basigin

1

4

High-throughput

0.618

High

787239

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.618

High

376539

LDLR
Low-density lipoprotein receptor

1

0

High-throughput

0.586

High

164426

NRP1
Neuropilin-1

1

20

High-throughput

0.575

High

396807

ESR1
Estrogen receptor

2

4

High-throughput

0.571

High

1359230

CA054
Uncharacterized protein C1orf54

2

5

High-throughput

0.549

High

1408465

FBX2
F-box only protein 2

2

9

High-throughput

0.549

High

506897

CFC1
Cryptic protein

1

3

High-throughput

0.536

High

518900

CCL3
C-C motif chemokine 3

1

1

High-throughput

0.536

High

567965

PRG2
Bone marrow proteoglycan

1

6

High-throughput

0.536

High

598272

CL3L1
C-C motif chemokine 3-like 1

1

1

High-throughput

0.536

High

933217

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

3

High-throughput

0.536

High

935788

MFAP4
Microfibril-associated glycoprotein 4

1

2

High-throughput

0.536

High

1116287

PTC1
Protein patched homolog 1

1

8

High-throughput

0.536

High

1408456

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

6

High-throughput

0.536

High

1408462

CBLN4
Cerebellin-4

1

6

High-throughput

0.536

High

1408464

DNJB9
DnaJ homolog subfamily B member 9

1

5

High-throughput

0.536

High

717588

PDIA3
Protein disulfide-isomerase A3

1

3

High-throughput

0.515

High

338672

VNN1
Pantetheinase

1

0

High-throughput

0.513

High

1209015

TTC38
Tetratricopeptide repeat protein 38

1

0

High-throughput

0.513

High

1249682

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.513

High

1308290

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

207870

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

1

High-throughput

0.489

High

342652

LY86
Lymphocyte antigen 86

1

3

High-throughput

0.489

High

942395

EP3B
Epididymal secretory protein E3-beta

1

1

High-throughput

0.489

High

1278797

HDGR2
Hepatoma-derived growth factor-related protein 2

1

3

High-throughput

0.489

High

1347289

FIBIN
Fin bud initiation factor homolog

1

2

High-throughput

0.489

High

1408459

SDF2L
Stromal cell-derived factor 2-like protein 1

1

5

High-throughput

0.489

High

218687

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

363779

EGFR
Epidermal growth factor receptor

1

10

High-throughput

0.479

High

411022

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

10

High-throughput

0.479

High

1108088

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1380725

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

616799

SDC1
Syndecan-1

1

1

High-throughput

0.445

High

1239922

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

872675

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.437

High

1367114

ESR2
Estrogen receptor beta

1

4

High-throughput

0.437

High

1136846

MO4L2
Mortality factor 4-like protein 2

1

0

High-throughput

0.426

High

1149677

SURF2
Surfeit locus protein 2

1

0

High-throughput

0.426

High

1408461

FBX6
F-box only protein 6

1

9

High-throughput

0.407

High

1396505

LCFC1
Sperm-egg fusion protein LLCFC1

1

0

High-throughput

0.279

Low

1408463

RBM28
RNA-binding protein 28

1

0

High-throughput

0.279

Low

1408466

EPDR1
Mammalian ependymin-related protein 1

1

0

High-throughput

0.279

Low

194313

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.249

Low

1408460

ANLN
Anillin

1

0

High-throughput

0.249

Low

288745

NPM3
Nucleoplasmin-3

1

0

High-throughput

0.232

Low

686371

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.232

Low

1037336

H11
Histone H1.1

1

0

High-throughput

0.232

Low

1278009

SZRD1
SUZ RNA-binding domain-containing

1

0

High-throughput

0.232

Low

1360146

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.232

Low

1408457

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025