HitPredict

Interactor 1: VP281 (O65421)
Vacuolar protein sorting-associated protein 28 homolog 1
Gene: VPS28-1

Interactor 2: ELC (Q9LHG8)
Protein ELC (AtELC) (ESCRT-I complex subunit VPS23 homolog 1) (Protein VACUOLAR PROTEIN SORTING 23A) (Vacuolar protein-sorting-associated protein 23 homolog 1)
Gene: ELC

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.837

Property	Details
Experiments	17090720, 21442383, 22639582
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	VPS28~Vps23_core
Common GO terms	GO:0000813 - ESCRT I complex
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 209 At			1 398
+	At
		1338040 VP282_ARATH (1-209): 1.49e-105: 303: 90.91		ELC_ARATH (1-398): 2.15e-178: 504: 100.00
+	At
		1322732 VP282_ARATH (1-209): 1.49e-105: 303: 90.91		ELCL_ARATH (1-398): 5.78e-159: 453: 69.67
+	At
		249669 VP281_ARATH (1-209): 4.12e-100: 290: 100.00		ELCL_ARATH (1-398): 5.78e-159: 453: 69.67
+	Hs
		1306614 VPS28_HUMAN (2-204): 3.14e-96: 280: 40.69		TS101_HUMAN (36-382): 4.28e-150: 431: 30.50
+	Dm
		1358229 VPS28_DROME (2-204): 2.43e-88: 260: 42.16		Q9VVA7_DROME (37-394): 1.13e-134: 393: 28.17
+	At
		96717 VP281_ARATH (1-209): 4.12e-100: 290: 100.00		F4ITY4_ARATH (13-378): 3.26e-119: 351: 26.76
+	Sc
		634967 VPS28_YEAST (2-204): 1.67e-72: 221: 37.05		STP22_YEAST (32-382): 1.94e-107: 322: 21.76
+	Dm
		1228853 VPS28_DROME (2-204): 2.43e-88: 260: 42.16		Q8MQZ0_DROME (37-233): 4.98e-73: 230: 28.31
+	At
		249672 VP281_ARATH (1-209): 4.12e-100: 290: 100.00		Q9SIH8_ARATH (243-378): 1.48e-47: 160: 29.41