Protein: EAA3
Excitatory amino acid transporter 3 (Excitatory amino-acid carrier 1) (Neuronal and epithelial glutamate transporter) (Sodium-dependent glutamate/aspartate transporter 3) (Solute carrier family 1 member 1)

Gene: EAA3, SLC1A1
Organism: Homo sapiens
Interactions: 176
UniProt ID: P43005

Gene Ontology (top 5):
GO:0001662 - behavioral fear response
GO:0001932 - regulation of protein phosphorylation
GO:0001975 - response to amphetamine
GO:0005253 - monoatomic anion channel activity
GO:0005313 - L-glutamate transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

792695

EAA1
Excitatory amino acid transporter 1

1

8

High-throughput

0.691

High

792744

SATT
Neutral amino acid transporter A

1

8

High-throughput

0.691

High

792868

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

3

High-throughput

0.691

High

792838

RNF5
E3 ubiquitin-protein ligase RNF5

3

1

High-throughput

0.675

High

121125

LEG8
Galectin-8

3

6

High-throughput

0.667

High

154321

TR10B
Tumor necrosis factor receptor superfamily member 10B

2

3

High-throughput

0.628

High

176403

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

2

1

High-throughput

0.628

High

234917

SNX3
Sorting nexin-3

2

1

High-throughput

0.628

High

507899

FGFR1
Fibroblast growth factor receptor 1

2

12

High-throughput

0.628

High

792758

RAB8A
Ras-related protein Rab-8A

2

3

High-throughput

0.628

High

792776

SNX17
Sorting nexin-17

2

2

High-throughput

0.628

High

792797

HACD2
Very-long-chain

2

1

High-throughput

0.628

High

792872

NUMBL
Numb-like protein

2

1

High-throughput

0.628

High

792772

SLAF1
Signaling lymphocytic activation molecule

2

2

High-throughput

0.611

High

792869

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

1

High-throughput

0.606

High

792794

C2D1A
Coiled-coil and C2 domain-containing protein 1A

2

0

High-throughput

0.602

High

792795

SBSN
Suprabasin

2

0

High-throughput

0.602

High

792800

GOGA7
Golgin subfamily A member 7

2

0

High-throughput

0.602

High

792811

ORML3
ORM1-like protein 3

2

0

High-throughput

0.602

High

792817

CHPT1
Cholinephosphotransferase 1

2

0

High-throughput

0.602

High

792827

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

2

0

High-throughput

0.602

High

792842

NFIP1
NEDD4 family-interacting protein 1

2

0

High-throughput

0.602

High

792857

NRN1
Neuritin

2

0

High-throughput

0.602

High

792858

CD320
CD320 antigen

2

0

High-throughput

0.602

High

792861

PXMP2
Peroxisomal membrane protein 2

2

0

High-throughput

0.602

High

792789

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

2

0

High-throughput

0.601

High

792743

EAA3
Excitatory amino acid transporter 3

1

8

Small-scale

0.584

High

792763

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.580

High

792774

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

792787

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

792801

T179B
Transmembrane protein 179B

2

0

High-throughput

0.580

High

316419

MPC2
Mitochondrial pyruvate carrier 2

2

1

High-throughput

0.574

High

792796

MIC27
MICOS complex subunit MIC27

2

1

High-throughput

0.574

High

792814

SYNPR
Synaptoporin

2

1

High-throughput

0.553

High

792765

EWS
RNA-binding protein EWS

1

1

High-throughput

0.541

High

277664

PRAF3
PRA1 family protein 3

1

0

Small-scale

0.537

High

156803

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

160911

RAB7L
Ras-related protein Rab-7L1

1

9

High-throughput

0.536

High

168172

PLCB
1-acyl-sn-glycerol-3-phosphate acyltransferase beta

1

1

High-throughput

0.536

High

175563

TM9S1
Transmembrane 9 superfamily member 1

1

1

High-throughput

0.536

High

212206

ERD23
ER lumen protein-retaining receptor 3

1

1

High-throughput

0.536

High

214753

PM34
Peroxisomal membrane protein PMP34

1

5

High-throughput

0.536

High

229639

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

1

High-throughput

0.536

High

234793

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

4

High-throughput

0.536

High

310539

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

2

High-throughput

0.536

High

316592

ACSL3
Fatty acid CoA ligase Acsl3

1

4

High-throughput

0.536

High

328312

S1PR4
Sphingosine 1-phosphate receptor 4

1

4

High-throughput

0.536

High

355021

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

3

High-throughput

0.536

High

518103

ADT1
ADP/ATP translocase 1

1

1

High-throughput

0.536

High

595522

GRAH
Granzyme H

1

1

High-throughput

0.536

High

616760

JAK1
Tyrosine-protein kinase JAK1

1

6

High-throughput

0.536

High

622656

ERD21
ER lumen protein-retaining receptor 1

1

1

High-throughput

0.536

High

674356

UFO
Tyrosine-protein kinase receptor UFO

1

10

High-throughput

0.536

High

677581

NTR1
Neurotensin receptor type 1

1

1

High-throughput

0.536

High

702608

ACSL1
Long-chain-fatty-acid--CoA ligase 1

1

4

High-throughput

0.536

High

792747

NUMB
Protein numb homolog

1

1

High-throughput

0.536

High

792748

PSN1
Presenilin-1

1

1

High-throughput

0.536

High

792753

VAMP7
Vesicle-associated membrane protein 7

1

2

High-throughput

0.536

High

792754

EPHA4
Ephrin type-A receptor 4

1

7

High-throughput

0.536

High

792769

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

1

High-throughput

0.536

High

792780

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

9

High-throughput

0.536

High

792781

CYTM
Cystatin-M

1

1

High-throughput

0.536

High

792790

ECM29
Proteasome adapter and scaffold protein ECM29

1

2

High-throughput

0.536

High

792793

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.536

High

792798

TBA1A
Tubulin alpha-1A chain

1

1

High-throughput

0.536

High

792799

COX15
Heme A synthase COX15

1

1

High-throughput

0.536

High

792803

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

1

High-throughput

0.536

High

792804

P2RY8
P2Y purinoceptor 8

1

4

High-throughput

0.536

High

792805

CHSS1
Chondroitin sulfate synthase 1

1

1

High-throughput

0.536

High

792822

TM9S4
Transmembrane 9 superfamily member 4

1

1

High-throughput

0.536

High

792823

LGAT1
Acyl-CoA:lysophosphatidylglycerol acyltransferase 1

1

1

High-throughput

0.536

High

792824

YIPF5
Protein YIPF5

1

2

High-throughput

0.536

High

792825

ARL8A
ADP-ribosylation factor-like protein 8A

1

2

High-throughput

0.536

High

792826

COQ8B
Atypical kinase COQ8B, mitochondrial

1

1

High-throughput

0.536

High

792828

YIPF6
Protein YIPF6

1

2

High-throughput

0.536

High

792846

ELOV1
Very long chain fatty acid elongase 1

1

1

High-throughput

0.536

High

792850

TSN10
Tetraspanin-10

1

2

High-throughput

0.536

High

792853

GHC1
Mitochondrial glutamate carrier 1

1

3

High-throughput

0.536

High

792860

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.536

High

49405

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

116665

UBXN8
UBX domain-containing protein 8

1

0

High-throughput

0.513

High

131880

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

173683

SURF4
Surfeit locus protein 4

1

0

High-throughput

0.513

High

179308

COPT2
Protein SLC31A2

1

0

High-throughput

0.513

High

217144

EXTL3
Exostosin-like 3

1

0

High-throughput

0.513

High

255298

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.513

High

380363

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.513

High

738436

ACV1B
Activin receptor type-1B

1

0

High-throughput

0.513

High

792745

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

0

High-throughput

0.513

High

792746

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.513

High

792750

CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform

1

0

High-throughput

0.513

High

792751

LRBA
Lipopolysaccharide-responsive and beige-like anchor protein

1

0

High-throughput

0.513

High

792755

BI1
Bax inhibitor 1

1

0

High-throughput

0.513

High

792756

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.513

High

792757

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

792760

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.513

High

792764

IFM3
Interferon-induced transmembrane protein 3

1

0

High-throughput

0.513

High

792767

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

792775

STAR3
StAR-related lipid transfer protein 3

1

0

High-throughput

0.513

High

792779

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

792782

D19L1
Protein C-mannosyl-transferase DPY19L1

1

0

High-throughput

0.513

High

792784

FND3B
Fibronectin type III domain-containing protein 3B

1

0

High-throughput

0.513

High

792786

YIF1B
Protein YIF1B

1

0

High-throughput

0.513

High

792791

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.513

High

792802

PP4P1
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

0

High-throughput

0.513

High

792806

VRK2
Serine/threonine-protein kinase VRK2

1

0

High-throughput

0.513

High

792807

K2C73
Keratin, type II cytoskeletal 73

1

0

High-throughput

0.513

High

792809

CKLF8
CKLF-like MARVEL transmembrane domain-containing protein 8

1

0

High-throughput

0.513

High

792810

VKORL
Vitamin K epoxide reductase complex subunit 1-like protein 1

1

0

High-throughput

0.513

High

792812

RELL2
RELT-like protein 2

1

0

High-throughput

0.513

High

792813

KCT2
Keratinocyte-associated transmembrane protein 2

1

0

High-throughput

0.513

High

792816

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.513

High

792819

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.513

High

792820

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.513

High

792821

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

792829

TV23C
Golgi apparatus membrane protein TVP23 homolog C

1

0

High-throughput

0.513

High

792830

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

792831

TM169
Transmembrane protein 169

1

0

High-throughput

0.513

High

792834

F210A
Protein FAM210A

1

0

High-throughput

0.513

High

792835

OPALI
Opalin

1

0

High-throughput

0.513

High

792836

TM209
Transmembrane protein 209

1

0

High-throughput

0.513

High

792837

SORT
Sortilin

1

0

High-throughput

0.513

High

792844

DERL1
Derlin-1

1

0

High-throughput

0.513

High

792845

PTSS2
Phosphatidylserine synthase 2

1

0

High-throughput

0.513

High

792848

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

792849

T126A
Transmembrane protein 126A

1

0

High-throughput

0.513

High

792851

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.513

High

792863

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.513

High

792864

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

792866

TMCO1
Calcium load-activated calcium channel

1

0

High-throughput

0.513

High

792871

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

0

High-throughput

0.513

High

394283

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

792770

DLG1
Disks large homolog 1

1

4

High-throughput

0.501

High

119232

LEG9
Galectin-9

1

6

High-throughput

0.489

High

792785

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.489

High

792792

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

3

High-throughput

0.489

High

792815

S2540
Mitochondrial glutathione transporter SLC25A40

1

6

High-throughput

0.489

High

792833

SFXN2
Sideroflexin-2

1

2

High-throughput

0.489

High

792841

S2533
Solute carrier family 25 member 33

1

4

High-throughput

0.489

High

792847

SFXN3
Sideroflexin-3

1

2

High-throughput

0.489

High

792852

CST9L
Cystatin-9-like

1

1

High-throughput

0.489

High

792856

TPC
Mitochondrial thiamine pyrophosphate carrier

1

3

High-throughput

0.489

High

792865

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

792867

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

1

High-throughput

0.489

High

792862

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

1

High-throughput

0.481

High

566319

KPCA
Protein kinase C alpha type

1

2

Small-scale

0.479

High

792752

RAB7A
Ras-related protein Rab-7a

1

6

High-throughput

0.479

High

792759

CXCR4
C-X-C chemokine receptor type 4

1

1

High-throughput

0.479

High

792761

RB11A
Ras-related protein Rab-11A

1

3

High-throughput

0.479

High

792762

DLG4
Disks large homolog 4

1

4

Small-scale

0.479

High

792766

NMDZ1
Glutamate receptor ionotropic, NMDA 1

1

4

Small-scale

0.479

High

792768

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

4

Small-scale

0.479

High

792771

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

4

Small-scale

0.479

High

672945

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.460

High

354347

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.445

High

359731

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

474459

GPHRB
Golgi pH regulator B

1

3

High-throughput

0.437

High

792783

MIDN
Midnolin

1

2

High-throughput

0.437

High

81798

GPHRA
Golgi pH regulator A

1

3

High-throughput

0.407

High

792808

MICU2
Calcium uptake protein 2, mitochondrial

2

0

High-throughput

0.328

High

265457

PAGE1
P antigen family member 1

2

0

High-throughput

0.316

High

792749

PPOX
Protoporphyrinogen oxidase

1

0

High-throughput

0.279

Low

792773

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.279

Low

792777

DPOD3
DNA polymerase delta subunit 3

1

0

High-throughput

0.279

Low

792778

OXA1L
Mitochondrial inner membrane protein OXA1L

1

0

High-throughput

0.279

Low

792788

SYRM
Probable arginine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

792818

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

0

High-throughput

0.279

Low

792832

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.279

Low

792839

MIC25
MICOS complex subunit MIC25

1

0

High-throughput

0.279

Low

792840

PGAP4
Post-GPI attachment to proteins factor 4

1

0

High-throughput

0.279

Low

792843

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.279

Low

792854

S61A2
Protein transport protein Sec61 subunit alpha isoform 2

1

0

High-throughput

0.279

Low

792855

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

High-throughput

0.279

Low

792859

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.279

Low

792870

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024