Interactor 1: NPHN (O60500)
Nephrin (Renal glomerulus-specific cell adhesion receptor)
Gene: NPHS1

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 25652011, 22662192
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0036057 - slit diaphragm
GO:0070062 - extracellular exosome
GO:0072015 - podocyte development
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1241
Hs

1 1657
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025