Protein: MMP14
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)

Gene: MMP14
Organism: Homo sapiens
Interactions: 60
UniProt ID: P50281

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001525 - angiogenesis
GO:0001541 - ovarian follicle development
GO:0001666 - response to hypoxia
GO:0001935 - endothelial cell proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

554808

TIMP2
Metalloproteinase inhibitor 2

6

20

Small-scale

0.950

High

344795

TIMP1
Metalloproteinase inhibitor 1

3

20

Small-scale

0.834

High

838537

TIMP4
Metalloproteinase inhibitor 4

2

20

Small-scale

0.812

High

838551

JAM1
Junctional adhesion molecule A

2

2

High-throughput

0.783

High

439268

MMP3
Stromelysin-1

1

4

Small-scale

0.692

High

726505

TIMP3
Metalloproteinase inhibitor 3

1

20

High-throughput

0.691

High

456827

FURIN
Furin

3

2

Small-scale

0.650

High

838511

LUM
Lumican

2

0

Small-scale

0.606

High

646144

STOM
Stomatin

2

0

High-throughput

0.580

High

838520

AQP6
Aquaporin-6

2

0

High-throughput

0.580

High

838521

FHL3
Four and a half LIM domains protein 3

2

0

High-throughput

0.580

High

838522

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

838523

MSMO1
Methylsterol monooxygenase 1

2

0

High-throughput

0.580

High

838528

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

838536

ZUP1
Zinc finger-containing ubiquitin peptidase 1

2

0

High-throughput

0.580

High

838517

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

Small-scale

0.561

High

838540

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.554

High

838513

RAD
GTP-binding protein RAD

1

1

High-throughput

0.541

High

838548

COR1C
Coronin-1C

1

0

Small-scale

0.537

High

427744

CO8A
Complement component C8 alpha chain

1

5

High-throughput

0.536

High

738734

SPB5
Serpin B5

1

3

High-throughput

0.536

High

838547

DKKL1
Dickkopf-like protein 1

1

1

High-throughput

0.536

High

838550

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.536

High

838534

LRC15
Leucine-rich repeat-containing protein 15

1

0

High-throughput

0.513

High

838539

MTND
Acireductone dioxygenase

1

0

Small-scale

0.506

High

436022

CO1A2
Collagen alpha-2(I) chain

1

17

Small-scale

0.501

High

838515

DEF1
Neutrophil defensin 1

1

1

Small-scale

0.501

High

838514

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

Small-scale

0.493

High

838524

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.493

High

838519

GALT1
Polypeptide N-acetylgalactosaminyltransferase 1

1

3

High-throughput

0.489

High

602232

CD9
CD9 antigen

1

1

High-throughput

0.484

High

602819

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

Small-scale

0.480

High

259270

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

2

Small-scale

0.479

High

346249

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

601479

FGFR2
Fibroblast growth factor receptor 2

1

4

Small-scale

0.479

High

607919

FGFR4
Fibroblast growth factor receptor 4

1

4

Small-scale

0.479

High

838512

LIMK1
LIM domain kinase 1

1

6

Small-scale

0.479

High

838518

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

2

Small-scale

0.479

High

838525

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

2

High-throughput

0.479

High

838527

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

838538

TICN3
Testican-3

1

4

Small-scale

0.479

High

838516

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

838544

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

152266

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

2

High-throughput

0.445

High

326271

TSN12
Tetraspanin-12

1

1

Small-scale

0.445

High

338135

EGFR
Epidermal growth factor receptor

1

4

High-throughput

0.445

High

838543

GORS2
Golgi reassembly-stacking protein 2

1

1

Small-scale

0.437

High

838529

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

838530

S15A4
Solute carrier family 15 member 4

1

0

Small-scale

0.426

High

838541

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.316

High

838531

KASH5
Protein KASH5

1

0

High-throughput

0.299

High

838549

PLLP
Plasmolipin

1

0

High-throughput

0.282

High

49313

T120B
Transmembrane protein 120B

1

0

High-throughput

0.279

Low

838532

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

838533

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

1

0

High-throughput

0.279

Low

838535

POF1B
Protein POF1B

1

0

High-throughput

0.279

Low

838542

TMX1
Thioredoxin-related transmembrane protein 1

1

0

High-throughput

0.279

Low

838545

CLDN1
Claudin domain-containing protein 1

1

0

High-throughput

0.279

Low

838526

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

838546

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024