HitPredict

Interactor 1: 1433S (O70456)
14-3-3 protein sigma (Stratifin)
Gene: Sfn

Interactor 2: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31040226
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Mm			1 1115
+	Mm
		250879 1433S_MOUSE (1-248): 3.26e-157: 437: 100.00		HDAC5_MOUSE (1-1115): 0: 788: 99.28
+	Mm
		910239 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		Q3UJF1_MOUSE (1-1115): 0: 796: 100.00
+	Mm
		910352 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		HDAC5_MOUSE (1-1115): 0: 788: 99.28
+	Hs
		684405 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC5_HUMAN (1-1115): 0: 760: 94.49
+	Hs
		910173 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC5_HUMAN (1-1115): 0: 760: 94.49
+	Hs
		683923 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC4_HUMAN (3-1095): 0: 697: 55.51
+	Hs
		880661 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC4_HUMAN (3-1095): 0: 697: 55.51
+	Hs
		684387 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC9_HUMAN (26-1048): 0: 641: 55.03
+	Hs
		910144 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC9_HUMAN (26-1048): 0: 641: 55.03
+	Hs
		646756 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		HDAC4_HUMAN (3-1095): 0: 697: 55.51
+	Hs
		684233 1433S_HUMAN (1-248): 4.84e-154: 429: 97.58		HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82
+	Hs
		909856 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC7_HUMAN (112-1115): 1.57e-169: 526: 40.82
+	Hs
		909530 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC1_HUMAN (666-1072): 2.18e-153: 467: 21.70
+	Dm
		664668 1433Z_DROME (1-240): 3.49e-136: 384: 65.83		Q9VYF3_DROME (137-1113): 2.67e-153: 491: 31.49
+	Hs
		177251 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC3_HUMAN (673-1112): 1.85e-147: 450: 21.04
+	Dm
		664611 1433Z_DROME (1-240): 3.49e-136: 384: 65.83		Q59E49_DROME (90-1113): 2.92e-144: 466: 30.14
+	At
		817061 14310_ARATH (2-247): 8.73e-138: 388: 54.03		HDA5_ARATH (671-1112): 2.34e-143: 447: 33.26
+	Hs
		910121 1433E_HUMAN (2-247): 1.43e-147: 413: 59.35		HDAC6_HUMAN (611-1061): 9.97e-109: 370: 31.77
+	Hs
		177204 1433T_HUMAN (1-238): 2.53e-109: 316: 73.11		HDAC3_HUMAN (673-1112): 1.85e-147: 450: 21.04
+	Mm
		910299 1433E_MOUSE (2-247): 1.43e-147: 413: 59.35		HDAC7_MOUSE (106-579): 1.31e-16: 87.4: 21.02