HitPredict

Interactor 1: RGA4 (O74360)
Probable Rho-type GTPase-activating protein 4
Gene: RGA4

Interactor 2: CDC42 (Q01112)
Cell division control protein 42 homolog (CDC42Sp)
Gene: CDC42

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	18328707, 20164182
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0097575 - lateral cell cortex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 933 Sp			1 192
+	Hs
		564562 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RHOQ_HUMAN (4-190): 1.13e-87: 258: 64.74
+	Sc
		580317 RGA1_YEAST (12-932): 7.36e-105: 351: 19.31		CDC42_YEAST (1-192): 4.57e-76: 228: 84.90
+	Hs
		925420 RHG12_HUMAN (149-933): 8.38e-99: 331: 14.88		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		925343 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		1133703 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RHOJ_HUMAN (4-189): 7.92e-81: 241: 61.83
+	Mm
		925793 ABR_MOUSE (122-933): 2.96e-94: 318: 11.65		RAC1_MOUSE (1-192): 3.29e-83: 246: 68.23
+	Hs
		545426 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RAC2_HUMAN (1-192): 1.33e-79: 236: 65.63
+	Hs
		925690 RHG23_HUMAN (131-933): 3.18e-89: 313: 13.85		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		900564 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RHOA_HUMAN (5-192): 2.36e-77: 231: 54.26
+	Hs
		951062 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RHOG_HUMAN (1-192): 1.47e-77: 231: 58.33
+	Hs
		894109 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25
+	Hs
		925378 RHG27_HUMAN (147-932): 7.42e-91: 310: 12.11		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		892420 RHG21_HUMAN (127-932): 2.05e-93: 327: 13.92		RAC3_HUMAN (1-191): 1.99e-76: 228: 67.54
+	Hs
		200213 SRGP3_HUMAN (280-932): 1.38e-86: 302: 13.29		RAC1_HUMAN (1-192): 3.29e-83: 246: 68.23
+	Hs
		900426 ABR_HUMAN (127-933): 1.16e-93: 317: 11.61		RHOA_HUMAN (5-192): 2.36e-77: 231: 54.26
+	Hs
		901000 RHG23_HUMAN (131-933): 3.18e-89: 313: 13.85		RHOA_HUMAN (5-192): 2.36e-77: 231: 54.26
+	Hs
		894152 RHG27_HUMAN (147-932): 7.42e-91: 310: 12.11		CDC42_HUMAN (1-192): 5.71e-77: 230: 81.25
+	Sc
		580332 RGA2_YEAST (12-932): 8.44e-90: 309: 15.70		CDC42_YEAST (1-192): 4.57e-76: 228: 84.90
+	Mm
		1265268 SRGP1_MOUSE (282-932): 4.95e-85: 297: 14.79		RHOA_MOUSE (5-192): 9.4e-78: 232: 53.72
+	Mm
		892733 SRGP1_MOUSE (282-932): 4.95e-85: 297: 14.79		CDC42_MOUSE (1-192): 5.71e-77: 230: 81.25