HitPredict

Interactor 1: RPN8 (O74440)
26S proteasome regulatory subunit rpn8
Gene: RPN8

Interactor 2: PSA4 (Q10329)
Probable proteasome subunit alpha type-4
Gene: pre6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20133687
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 324 Sp			1 259
+	Dm
		640776 PSMD7_DROME (8-323): 4.25e-102: 304: 47.81		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Dm
		611629 PSMD7_DROME (8-323): 4.25e-102: 304: 47.81		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Hs
		637362 PSMD7_HUMAN (13-302): 1e-97: 293: 52.58		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Mm
		643130 PSMD7_MOUSE (13-302): 4.07e-98: 294: 52.92		PSA1_MOUSE (2-259): 1.99e-93: 277: 27.65
+	Hs
		656177 PSMD7_HUMAN (13-302): 1e-97: 293: 52.58		PSA5_HUMAN (2-232): 7.74e-94: 277: 34.03
+	Sc
		771389 RPN8_YEAST (15-324): 1.39e-95: 288: 50.94		PSA4_YEAST (1-232): 5.22e-93: 275: 58.48
+	Sc
		689214 RPN8_YEAST (15-324): 1.39e-95: 288: 50.94		PSA5_YEAST (2-245): 1.62e-91: 272: 32.54
+	Hs
		849173 PSMD7_HUMAN (13-302): 1e-97: 293: 52.58		PSA6_HUMAN (2-236): 7.16e-90: 267: 29.88
+	Sp
		784770 RPN11_SCHPO (5-225): 1.44e-55: 184: 17.86		PSA4_SCHPO (1-259): 2.44e-102: 299: 100.00
+	Dm
		640767 PSMD7_DROME (8-323): 4.25e-102: 304: 47.81		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Sp
		784781 RPN11_SCHPO (5-225): 1.44e-55: 184: 17.86		PSA5_SCHPO (2-237): 5.79e-94: 278: 32.79
+	Dm
		1278634 PSDE_DROME (6-227): 2.78e-54: 181: 17.53		PSA5_DROME (2-233): 1.76e-93: 277: 34.44
+	Dm
		611650 PSDE_DROME (6-227): 2.78e-54: 181: 17.53		PSA71_DROME (2-229): 8.62e-91: 270: 52.61
+	Sp
		784767 RPN11_SCHPO (5-225): 1.44e-55: 184: 17.86		PSA3_SCHPO (1-238): 2.11e-89: 266: 32.26
+	Hs
		637651 PSMD7_HUMAN (13-302): 1e-97: 293: 52.58		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10
+	Hs
		130644 PSDE_HUMAN (6-139): 2.91e-21: 93.7: 24.46		PSA7_HUMAN (4-230): 8.52e-97: 285: 54.59
+	Hs
		130746 PSDE_HUMAN (6-139): 2.91e-21: 93.7: 24.46		PSA1_HUMAN (2-259): 1.01e-93: 278: 27.27
+	Dm
		771306 PSDE_DROME (6-227): 2.78e-54: 181: 17.53		PSA2_DROME (4-212): 3.06e-48: 161: 37.92
+	Sp
		293712 RPN11_SCHPO (5-225): 1.44e-55: 184: 17.86		PSA2_SCHPO (4-211): 2.04e-44: 151: 37.44
+	Hs
		130747 PSDE_HUMAN (6-139): 2.91e-21: 93.7: 24.46		PSA2_HUMAN (3-210): 2.47e-45: 153: 38.10