HitPredict

Interactor 1: ASF1 (O74515)
Histone chaperone cia1 (Anti-silencing function protein 1)
Gene: cia1

Interactor 2: HIR1 (P87314)
Protein hir1 (Histone transcription regulator 1 homolog)
Gene: hip1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	18334479, 21211723
Identification Methods	x-ray crystallography, affinity chromatography technology
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	ASF1_hist_chap~HIRA_B
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0006338 - chromatin remodeling
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 262 Sp			1 932
+	Hs
		867897 ASF1B_HUMAN (1-161): 2.22e-98: 287: 54.04		HIRA_HUMAN (1-927): 1.87e-131: 422: 20.98
+	Hs
		867906 ASF1A_HUMAN (1-182): 1.14e-94: 278: 48.91		HIRA_HUMAN (1-927): 1.87e-131: 422: 20.98
+	Xl
		1148535 AS1AA_XENLA (1-169): 6.87e-95: 278: 52.63		HIRA_XENLA (1-927): 3.06e-128: 413: 21.42
+	Dm
		184546 ASF1_DROME (1-160): 4.55e-90: 267: 52.50		HIRA_DROME (1-931): 2.37e-131: 423: 21.95
+	Gg
		945614 ASF1_CHICK (1-182): 1.14e-94: 278: 48.91		HIRA_CHICK (1-927): 2.43e-103: 347: 20.91
+	Gg
		1107997 ASF1_CHICK (1-182): 1.14e-94: 278: 48.91		CAF1B_CHICK (1-540): 2.27e-90: 300: 21.75
+	Hs
		1024600 ASF1B_HUMAN (1-161): 2.22e-98: 287: 54.04		CAF1B_HUMAN (1-537): 5.63e-86: 288: 21.70
+	Sc
		689846 ASF1_YEAST (1-172): 9.83e-83: 250: 63.01		HIR1_YEAST (1-768): 4.15e-95: 320: 30.38
+	Hs
		1024612 ASF1A_HUMAN (1-182): 1.14e-94: 278: 48.91		CAF1B_HUMAN (1-537): 5.63e-86: 288: 21.70
+	Dm
		53064 ASF1_DROME (1-160): 4.55e-90: 267: 52.50		A1Z898_DROME (2-603): 1.03e-80: 279: 20.06
+	Xl
		993165 AS1AA_XENLA (1-169): 6.87e-95: 278: 52.63		Q07CZ6_XENLA (1-546): 2.59e-78: 267: 18.95
+	Sc
		689847 ASF1_YEAST (1-172): 9.83e-83: 250: 63.01		HIR2_YEAST (1-927): 1.33e-84: 292: 20.33
+	Sc
		689955 ASF1_YEAST (1-172): 9.83e-83: 250: 63.01		CAC2_YEAST (11-365): 5.47e-71: 244: 20.72
+	Sp
		251229 ASF1_SCHPO (1-174): 1.14e-97: 288: 100.00		SLM9_SCHPO (5-202): 5.73e-18: 91.4: 14.42
+	Sp
		144001 ASF1_SCHPO (1-174): 1.14e-97: 288: 100.00		YEG3_SCHPO (2-207): 9.42e-18: 89.7: 27.89
+	Hs
		1288338 ASF1B_HUMAN (1-161): 2.22e-98: 287: 54.04		SNR40_HUMAN (582-783): 6.93e-14: 76.4: 8.41
+	At
		1321245 ASF1A_ARATH (1-203): 1.56e-86: 257: 44.83		HIRA_ARATH (360-719): 1.17e-15: 84.1: 7.69