HitPredict

Interactor 1: RHP23 (O74803)
UV excision repair protein rhp23 (RAD23 homolog)
Gene: RHP23

Interactor 2: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.834

Property	Details
Experiments	12615927, 11584278, 20614012
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 368 Sp			1 891
+	Rn
		1116239 RD23B_RAT (1-365): 4.86e-98: 298: 31.40		PSMD2_RAT (1-885): 0: 1237: 48.02
+	Hs
		872262 RD23B_HUMAN (1-365): 1.65e-94: 289: 31.84		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		872151 RD23A_HUMAN (1-365): 8.95e-88: 270: 33.25		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	At
		1195577 RD23C_ARATH (1-366): 3.6e-98: 299: 29.98		PSD2A_ARATH (3-885): 0: 1148: 46.77
+	Hs
		1027821 UBQL1_HUMAN (1-338): 1.22e-51: 182: 12.85		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		1027815 UBQL2_HUMAN (3-338): 2.6e-47: 171: 11.61		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		1027806 UBQL4_HUMAN (1-338): 3.72e-46: 168: 10.92		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	At
		1091720 UBQ3_ARATH (1-78): 2.67e-32: 124: 25.64		PSD2B_ARATH (46-885): 0: 1142: 47.25
+	Dm
		1362832 Q9VCD5_DROME (1-366): 5.62e-59: 194: 25.82		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Dm
		1374998 Q9VWD9_DROME (2-332): 6.77e-56: 193: 13.91		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Sc
		697080 RAD23_YEAST (1-363): 4.47e-80: 252: 34.41		RPN1_YEAST (50-885): 0: 901: 39.42
+	Rn
		292215 RD23B_RAT (1-365): 4.86e-98: 298: 31.40		PSMD1_RAT (141-826): 6.72e-170: 520: 19.32
+	Hs
		872303 RD23B_HUMAN (1-365): 1.65e-94: 289: 31.84		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		872202 RD23A_HUMAN (1-365): 8.95e-88: 270: 33.25		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Sc
		693266 RAD23_YEAST (1-363): 4.47e-80: 252: 34.41		RPN2_YEAST (60-822): 4.16e-145: 455: 18.37
+	Hs
		1303954 UBQL1_HUMAN (1-338): 1.22e-51: 182: 12.85		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		1303948 UBQL2_HUMAN (3-338): 2.6e-47: 171: 11.61		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Hs
		1303937 UBQL4_HUMAN (1-338): 3.72e-46: 168: 10.92		PSMD1_HUMAN (141-826): 6.09e-171: 522: 19.43
+	Dm
		1359018 Q9VWD9_DROME (2-332): 6.77e-56: 193: 13.91		PSMD1_DROME (370-819): 2.85e-141: 447: 21.91
+	At
		221381 UBQ3_ARATH (1-78): 2.67e-32: 124: 25.64		PSD1A_ARATH (347-819): 3.16e-159: 493: 23.05