Protein: VP33B
Vacuolar protein sorting-associated protein 33B (hVPS33B)

Gene: VP33B, VPS33B
Organism: Homo sapiens
Interactions: 183
UniProt ID: Q9H267

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005770 - late endosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1431541

SPE39
Spermatogenesis-defective protein 39 homolog

14

10

Small-scale

0.987

High

189830

STX7
Syntaxin-7

2

20

Small-scale

0.743

High

1138047

TNIP1
TNFAIP3-interacting protein 1

4

8

High-throughput

0.705

High

257175

CCD22
Coiled-coil domain-containing protein 22

3

4

High-throughput

0.689

High

1233231

Q6IA61
Spermatogenesis-defective protein 39 homolog

1

10

High-throughput

0.665

High

702159

ITPI2
Protein ITPRID2

3

0

High-throughput

0.638

High

246135

KIF1B
Kinesin-like protein KIF1B

2

6

High-throughput

0.628

High

1315206

GT252
Procollagen galactosyltransferase 2

2

1

High-throughput

0.628

High

226196

STX6
Syntaxin-6

1

12

High-throughput

0.618

High

280334

SC22B
Vesicle-trafficking protein SEC22b

1

13

High-throughput

0.618

High

1431565

MTMR7
Phosphatidylinositol-3-phosphate phosphatase MTMR7

2

2

High-throughput

0.611

High

1278363

COMD6
COMM domain-containing protein 6

2

0

High-throughput

0.602

High

1328846

COMD1
COMM domain-containing protein 1

2

0

High-throughput

0.602

High

888814

VPS41
Vacuolar protein sorting-associated protein 41 homolog

2

17

Small-scale

0.584

High

976552

RB11A
Ras-related protein Rab-11A

2

5

High-throughput

0.584

High

1322446

SPICE
Spindle and centriole-associated protein 1

2

1

High-throughput

0.584

High

337515

MATN4
Matrilin-4

2

2

High-throughput

0.574

High

251964

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

1

High-throughput

0.536

High

730231

1433B
14-3-3 protein beta/alpha

1

2

High-throughput

0.536

High

1404390

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

1420055

KPCD2
Serine/threonine-protein kinase D2

1

6

High-throughput

0.536

High

1431570

CHMP3
Charged multivesicular body protein 3

1

1

High-throughput

0.536

High

1431573

WASF2
Actin-binding protein WASF2

1

2

High-throughput

0.536

High

390757

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.515

High

281482

MSPD3
Motile sperm domain-containing protein 3

1

0

High-throughput

0.513

High

1431551

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

1

High-throughput

0.508

High

423143

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

1217282

VPS53
Vacuolar protein sorting-associated protein 53 homolog

1

0

High-throughput

0.493

High

1103733

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.486

High

60413

NBAS
NBAS subunit of NRZ tethering complex

1

1

High-throughput

0.479

High

124965

GTPB1
GTP-binding protein 1

1

2

High-throughput

0.479

High

126792

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

128063

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

3

High-throughput

0.479

High

128319

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

2

High-throughput

0.479

High

141657

DDX3X
ATP-dependent RNA helicase DDX3X

1

2

High-throughput

0.479

High

158881

AP3D1
AP-3 complex subunit delta-1

1

6

Small-scale

0.479

High

169746

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

5

Small-scale

0.479

High

211046

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

1

High-throughput

0.479

High

218757

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

270738

N4BP1
NEDD4-binding protein 1

1

1

High-throughput

0.479

High

324211

CE152
Centrosomal protein of 152 kDa

1

1

High-throughput

0.479

High

346313

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

348197

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

1

High-throughput

0.479

High

373123

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

412589

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

483392

CLCB
Clathrin light chain B

1

1

Small-scale

0.479

High

540668

LAMP1
Lysosome-associated membrane glycoprotein 1

1

8

High-throughput

0.479

High

611341

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

630966

RAB4A
Ras-related protein Rab-4A

1

12

High-throughput

0.479

High

755626

TTK
Dual specificity protein kinase TTK

1

6

High-throughput

0.479

High

901558

RAB7A
Ras-related protein Rab-7a

1

16

High-throughput

0.479

High

927543

ATX1
Ataxin-1

1

2

High-throughput

0.479

High

955576

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

962823

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

996848

TBA1B
Tubulin alpha-1B chain

1

1

High-throughput

0.479

High

1010873

TMF1
TATA element modulatory factor

1

3

High-throughput

0.479

High

1015770

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1065763

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

5

High-throughput

0.479

High

1091458

ANK3
Ankyrin-3

1

1

High-throughput

0.479

High

1095587

LIPA1
Liprin-alpha-1

1

3

High-throughput

0.479

High

1132533

NAA30
N-alpha-acetyltransferase 30

1

1

High-throughput

0.479

High

1135379

SLMAP
Sarcolemmal membrane-associated protein

1

5

High-throughput

0.479

High

1136596

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

3

High-throughput

0.479

High

1140839

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

1151866

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1191482

GRDN
Girdin

1

4

High-throughput

0.479

High

1196320

GRAP1
GRIP1-associated protein 1

1

3

High-throughput

0.479

High

1206143

TGO1
Transport and Golgi organization protein 1 homolog

1

2

High-throughput

0.479

High

1213191

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

2

High-throughput

0.479

High

1214953

CCD18
Coiled-coil domain-containing protein 18

1

2

High-throughput

0.479

High

1219661

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

1

High-throughput

0.479

High

1225383

WAC2A
WASH complex subunit 2A

1

1

High-throughput

0.479

High

1227437

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.479

High

1233474

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1251267

DNMBP
Dynamin-binding protein

1

7

High-throughput

0.479

High

1255495

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1256588

CE128
Centrosomal protein of 128 kDa

1

6

High-throughput

0.479

High

1258310

MOB2
MOB kinase activator 2

1

1

High-throughput

0.479

High

1276311

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1278928

BRAP
BRCA1-associated protein

1

1

High-throughput

0.479

High

1286542

PHLB2
Pleckstrin homology-like domain family B member 2

1

1

High-throughput

0.479

High

1292194

LIPB1
Liprin-beta-1

1

4

High-throughput

0.479

High

1329351

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

3

High-throughput

0.479

High

1348318

GOGA5
Golgin subfamily A member 5

1

3

High-throughput

0.479

High

1351417

CABL1
CDK5 and ABL1 enzyme substrate 1

1

1

High-throughput

0.479

High

1359451

LMO7
LIM domain only protein 7

1

1

High-throughput

0.479

High

1360670

SYNE2
Nesprin-2

1

7

High-throughput

0.479

High

1361156

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.479

High

1368112

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

1371065

ARHG2
Rho guanine nucleotide exchange factor 2

1

3

High-throughput

0.479

High

1387725

TBC31
TBC1 domain family member 31

1

2

High-throughput

0.479

High

1387823

ATG4C
Cysteine protease ATG4C

1

1

High-throughput

0.479

High

1388681

ELP4
Elongator complex protein 4

1

1

High-throughput

0.479

High

1395765

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

1

3

High-throughput

0.479

High

1396260

ASPP1
Apoptosis-stimulating of p53 protein 1

1

5

High-throughput

0.479

High

1402518

NEB2
Neurabin-2

1

3

High-throughput

0.479

High

1403781

RMD3
Regulator of microtubule dynamics protein 3

1

1

High-throughput

0.479

High

1411293

LZTS2
Leucine zipper putative tumor suppressor 2

1

5

High-throughput

0.479

High

1431536

CUED2
CUE domain-containing protein 2

1

1

High-throughput

0.479

High

1431537

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.479

High

1431542

PKHA5
Pleckstrin homology domain-containing family A member 5

1

8

High-throughput

0.479

High

1431544

NCK5L
Nck-associated protein 5-like

1

1

High-throughput

0.479

High

1431545

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

1

High-throughput

0.479

High

1431550

OCAD1
OCIA domain-containing protein 1

1

1

High-throughput

0.479

High

1431553

ARHGC
Rho guanine nucleotide exchange factor 12

1

5

High-throughput

0.479

High

1431554

CHMP5
Charged multivesicular body protein 5

1

1

High-throughput

0.479

High

1431556

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.479

High

1431557

RBM27
RNA-binding protein 27

1

2

High-throughput

0.479

High

1431558

HECW2
E3 ubiquitin-protein ligase HECW2

1

1

High-throughput

0.479

High

1431559

UVRAG
UV radiation resistance-associated gene protein

1

1

Small-scale

0.479

High

1431560

VPS51
Vacuolar protein sorting-associated protein 51 homolog

1

1

High-throughput

0.479

High

1431562

RAB21
Ras-related protein Rab-21

1

15

High-throughput

0.479

High

1431563

PKHG1
Pleckstrin homology domain-containing family G member 1

1

3

High-throughput

0.479

High

1431564

CP131
Centrosomal protein of 131 kDa

1

1

High-throughput

0.479

High

1431568

NINL
Ninein-like protein

1

5

High-throughput

0.479

High

1431569

PHOCN
MOB-like protein phocein

1

1

High-throughput

0.479

High

1431571

C170B
Centrosomal protein of 170 kDa protein B

1

1

High-throughput

0.479

High

1431572

CEP83
Centrosomal protein of 83 kDa

1

3

High-throughput

0.479

High

64117

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

159264

ABLM1
Actin-binding LIM protein 1

1

0

High-throughput

0.458

High

208733

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.458

High

254225

CTND1
Catenin delta-1

1

0

High-throughput

0.458

High

290149

OFD1
Centriole and centriolar satellite protein OFD1

1

0

High-throughput

0.458

High

896305

PEX5
Peroxisomal targeting signal 1 receptor

1

0

High-throughput

0.458

High

979228

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

991931

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.458

High

1098752

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.458

High

1137007

SEPT2
Septin-2

1

0

High-throughput

0.458

High

1143529

PCM1
Pericentriolar material 1 protein

1

0

High-throughput

0.458

High

1144874

RABE1
Rab GTPase-binding effector protein 1

1

0

High-throughput

0.458

High

1169033

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.458

High

1178010

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1191613

RABL6
Rab-like protein 6

1

0

High-throughput

0.458

High

1217503

CE350
Centrosome-associated protein 350

1

0

High-throughput

0.458

High

1329996

TEX9
Testis-expressed protein 9

1

0

High-throughput

0.458

High

1359539

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

1362005

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

Small-scale

0.458

High

1363971

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1385693

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.458

High

1390405

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.458

High

1405211

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1421210

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.458

High

1429563

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.458

High

1431534

DHX36
ATP-dependent DNA/RNA helicase DHX36

1

0

High-throughput

0.458

High

1431535

CA198
Uncharacterized protein C1orf198

1

0

High-throughput

0.458

High

1431539

TDRD3
Tudor domain-containing protein 3

1

0

High-throughput

0.458

High

1431540

CCSE2
Serine-rich coiled-coil domain-containing protein 2

1

0

High-throughput

0.458

High

1431543

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.458

High

1431546

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.458

High

1431549

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.458

High

1431552

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1431561

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.458

High

1431566

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.458

High

1431567

ADIP
Afadin- and alpha-actinin-binding protein

1

0

High-throughput

0.458

High

322866

MTCL2
Microtubule cross-linking factor 2

1

4

High-throughput

0.437

High

589658

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

696475

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.437

High

710481

EPHA2
Ephrin type-A receptor 2

1

11

High-throughput

0.437

High

769145

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

1100368

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

1216525

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

4

High-throughput

0.437

High

1258940

H32
Histone H3.2

1

1

High-throughput

0.437

High

1276773

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

3

High-throughput

0.437

High

1277069

CC186
Coiled-coil domain-containing protein 186

1

2

High-throughput

0.437

High

1310645

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

3

High-throughput

0.437

High

1312251

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.437

High

1326338

NIN
Ninein

1

6

High-throughput

0.437

High

1353013

SNX29
Sorting nexin-29

1

2

High-throughput

0.437

High

1431533

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

1

High-throughput

0.437

High

1431547

HELLS
Lymphoid-specific helicase

1

2

High-throughput

0.437

High

1431548

ATD3A
ATPase family AAA domain-containing protein 3A

1

4

High-throughput

0.437

High

1431555

HACD3
Very-long-chain

1

2

High-throughput

0.437

High

1286408

LYG2
Lysozyme g-like protein 2

2

0

High-throughput

0.328

High

553068

PIP
Prolactin-inducible protein

1

0

High-throughput

0.279

Low

1111262

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.279

Low

1309885

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.249

Low

1340417

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.249

Low

1340933

NCOA7
Nuclear receptor coactivator 7

1

0

High-throughput

0.249

Low

1350139

SPP
Signal peptide peptidase

1

0

High-throughput

0.249

Low

1397834

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1398947

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.249

Low

1431538

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.249

Low

344318

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025